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1.
Blocking TNF signaling may save lives in COVID-19 infection.
Mol Biol Rep
; 49(3): 2303-2309, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-35076845
2.
Anti-TL1A Antibody PF-06480605 Safety and Efficacy for Ulcerative Colitis: A Phase 2a Single-Arm Study.
Clin Gastroenterol Hepatol
; 19(11): 2324-2332.e6, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34126262
3.
First-in-human, randomized dose-escalation study of the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of PF-06480605 in healthy subjects.
Br J Clin Pharmacol
; 86(4): 812-824, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31758576
4.
Addressing Domain Specificity in the Development of a Cell-Based Binding Assay for the Detection of Neutralizing Antibodies Against a CD47xPD-L1 Bispecific Antibody.
AAPS J
; 25(6): 91, 2023 09 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-37740131
5.
Determination of Anti-drug Antibody Affinity in Clinical Study Samples Provides a Tool for Evaluation of Immune Response Maturation.
AAPS J
; 24(6): 114, 2022 11 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36324032
6.
Antitumor Necrosis Factor-like Ligand 1A Therapy Targets Tissue Inflammation and Fibrosis Pathways and Reduces Gut Pathobionts in Ulcerative Colitis.
Inflamm Bowel Dis
; 28(3): 434-446, 2022 03 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34427649
7.
Fit-for-Purpose Validation and Establishment of Assay Acceptance and Reporting Criteria of Dendritic Cell Activation Assay Contributing to the Assessment of Immunogenicity Risk.
AAPS J
; 22(5): 114, 2020 08 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32839919
8.
A universal strategy for development of a method for absolute quantification of therapeutic monoclonal antibodies in biological matrices using differential dimethyl labeling coupled with ultra performance liquid chromatography-tandem mass spectrometry.
Anal Chem
; 81(22): 9321-8, 2009 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19842637
9.
Development and validation of an LC-MS/MS method for quantification of cyclic guanosine 3',5'-monophosphate (cGMP) in clinical applications: a comparison with a EIA method.
J Chromatogr B Analyt Technol Biomed Life Sci
; 877(5-6): 513-20, 2009 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19179124
10.
Anti-drug Antibody Assay Conditions Significantly Impact Assay Screen and Confirmatory Cut-Points.
AAPS J
; 21(4): 71, 2019 06 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31161482
11.
Absolute quantification of multidrug resistance-associated protein 2 (MRP2/ABCC2) using liquid chromatography tandem mass spectrometry.
Anal Biochem
; 380(2): 211-22, 2008 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18558078
12.
Mucosal Gene Expression in Pediatric and Adult Patients With Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic Analysis.
Inflamm Bowel Dis
; 24(12): 2565-2578, 2018 11 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-30085215
13.
Physiologically relevant binding affinity quantification of monoclonal antibody PF-00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlation.
Br J Pharmacol
; 174(1): 70-81, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27760281
14.
Implementation of an ADME enabling selection and visualization tool for drug discovery.
J Pharm Sci
; 93(5): 1131-41, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15067690
15.
Mechanism-based pharmacokinetic/pharmacodynamic modeling of rat prefrontal cortical dopamine response to dual acting norepinephrine reuptake inhibitor and 5-HT1A partial agonist.
AAPS J
; 14(2): 365-76, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22454087
16.
The development and validation of a computational model to predict rat liver microsomal clearance.
J Pharm Sci
; 98(8): 2857-67, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19116953
17.
Diethylation labeling combined with UPLC/MS/MS for simultaneous determination of a panel of monoamine neurotransmitters in rat prefrontal cortex microdialysates.
Anal Chem
; 80(23): 9195-203, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19551941
18.
Effects of organic anion, organic cation, and dipeptide transport inhibitors on cefdinir in the isolated perfused rat kidney.
Antimicrob Agents Chemother
; 47(2): 689-96, 2003 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-12543679
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