Detalles de la búsqueda
1.
A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer.
Prostate
; 84(6): 605-619, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38375594
2.
Mechanistic study of dual-function inhibitors targeting topoisomerase II and Rad51-mediated DNA repair pathway against castration-resistant prostate cancer.
Prostate
; 83(16): 1549-1563, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37583103
3.
Antileukemic Natural Product Induced Both Apoptotic and Pyroptotic Programmed Cell Death and Differentiation Effect.
Int J Mol Sci
; 22(20)2021 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34681898
4.
Autophagic Activation and Decrease of Plasma Membrane Cholesterol Contribute to Anticancer Activities in Non-Small Cell Lung Cancer.
Molecules
; 26(19)2021 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34641511
5.
Ascleposide, a natural cardenolide, induces anticancer signaling in human castration-resistant prostatic cancer through Na+ /K+ -ATPase internalization and tubulin acetylation.
Prostate
; 80(4): 305-318, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31905252
6.
Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells-Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy.
Int J Mol Sci
; 21(7)2020 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32252439
7.
Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death Against Human Non-Small Cell Lung Cancers.
Int J Mol Sci
; 21(16)2020 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32764382
8.
Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies.
Molecules
; 25(24)2020 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33339319
9.
The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis.
Molecules
; 25(12)2020 Jun 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32630532
10.
Moniliformediquinone induces in vitro and in vivo antitumor activity through glutathione involved DNA damage response and mitochondrial stress in human hormone refractory prostate cancer.
J Urol
; 191(5): 1429-38, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24316097
11.
Doxazosin inhibits vasculogenic mimicry in human nonsmall cell lung cancer through inhibition of the VEGFA/VEcadherin/mTOR/MMP pathway.
Oncol Lett
; 27(4): 170, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38455663
12.
Cardenolide glycosides sensitize gefitinib-induced apoptosis in non-small cell lung cancer: inhibition of Na+/K+-ATPase serving as a switch-on mechanism.
Naunyn Schmiedebergs Arch Pharmacol
; 2024 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38451282
13.
The Combination of a Novel GLUT1 Inhibitor and Cisplatin Synergistically Inhibits Breast Cancer Cell Growth By Enhancing the DNA Damaging Effect and Modulating the Akt/mTOR and MAPK Signaling Pathways.
Front Pharmacol
; 13: 879748, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35662690
14.
Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling.
Front Oncol
; 10: 1274, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32850387
15.
Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells.
Front Pharmacol
; 11: 599067, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33343369
16.
Extract From Plectranthus amboinicus Inhibit Maturation and Release of Interleukin 1ß Through Inhibition of NF-κB Nuclear Translocation and NLRP3 Inflammasome Activation.
Front Pharmacol
; 10: 573, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31191313
17.
Para-Toluenesulfonamide Induces Anti-tumor Activity Through Akt-Dependent and -Independent mTOR/p70S6K Pathway: Roles of Lipid Raft and Cholesterol Contents.
Front Pharmacol
; 9: 1223, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30555320
18.
Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Repair Systems.
Front Oncol
; 8: 681, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30705876
19.
Enantiomerically pure ß-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathways.
Oncotarget
; 8(57): 96668-96683, 2017 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-29228561
20.
Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: the role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways.
Oncotarget
; 7(47): 76995-77009, 2016 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27769069