Detalles de la búsqueda
1.
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.
Bioorg Med Chem
; 22(19): 5241-8, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25199582
2.
Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission.
J Antimicrob Chemother
; 68(9): 2038-47, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23645585
3.
Synthesis, evaluation and structure-activity relationships of triazine dimers as novel antiviral agents.
Bioorg Med Chem Lett
; 22(23): 7174-8, 2012 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23084903
4.
Novel diarylpyridinones, diarylpyridazinones and diarylphthalazinones as potential HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs).
Bioorg Med Chem
; 19(20): 5924-34, 2011 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21930388
5.
High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: strategic flexibility explains potency against resistance mutations.
Proc Natl Acad Sci U S A
; 105(5): 1466-71, 2008 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-18230722
6.
The pregnancy and long-term neurodevelopmental outcome of monochorionic diamniotic twin gestations: a multicenter prospective cohort study from the first trimester onward.
Am J Obstet Gynecol
; 200(5): 494.e1-8, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19375567
7.
The effect of maternal betamethasone and fetal tracheal occlusion on pulmonary vascular morphometry in fetal rabbits with surgically induced diaphragmatic hernia: a placebo controlled morphologic study.
Prenat Diagn
; 29(7): 674-81, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19365875
8.
Novel triazine dimers with potent antitrypanosomal activity.
Eur J Med Chem
; 143: 306-319, 2018 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29197735
9.
In vitro pre- and post-exposure prophylaxis using HIV inhibitors as microbicides against cell-free or cell-associated HIV-1 infection.
Antivir Chem Chemother
; 18(3): 141-51, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17626598
10.
Crystallography and the design of anti-AIDS drugs: conformational flexibility and positional adaptability are important in the design of non-nucleoside HIV-1 reverse transcriptase inhibitors.
Prog Biophys Mol Biol
; 88(2): 209-31, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15572156
11.
Stereotypy in schizophrenia.
Schizophr Res
; 84(2-3): 397-404, 2006 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-16549339
12.
Pre-incubation of cell-free HIV-1 group M isolates with non-nucleoside reverse transcriptase inhibitors blocks subsequent viral replication in co-cultures of dendritic cells and T cells.
Antivir Ther
; 10(2): 255-62, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15865220
13.
Concentration and pH dependent aggregation of hydrophobic drug molecules and relevance to oral bioavailability.
J Med Chem
; 48(6): 1974-83, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771441
14.
Structure based activity prediction of HIV-1 reverse transcriptase inhibitors.
J Med Chem
; 48(6): 2176-83, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771460
15.
In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine).
J Med Chem
; 48(6): 1901-9, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771434
16.
Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity.
J Med Chem
; 48(6): 1910-8, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771435
17.
Synthesis of novel diarylpyrimidine analogues and their antiviral activity against human immunodeficiency virus type 1.
J Med Chem
; 48(6): 2072-9, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771449
18.
SYNOPSIS: SYNthesize and OPtimize System in Silico.
J Med Chem
; 46(13): 2765-73, 2003 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-12801239
19.
Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants.
J Med Chem
; 47(10): 2550-60, 2004 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-15115397
20.
Development and in vitro evaluation of a vaginal microbicide gel formulation for UAMC01398, a novel diaryltriazine NNRTI against HIV-1.
Antiviral Res
; 101: 113-21, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24269474