Detalles de la búsqueda
1.
Fibroblast growth factor receptor 1/Klothoß agonist BFKB8488A improves lipids and liver health markers in patients with diabetes or NAFLD: A phase 1b randomized trial.
Hepatology
; 78(3): 847-862, 2023 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35993161
2.
Antibody-mediated activation of the FGFR1/Klothoß complex corrects metabolic dysfunction and alters food preference in obese humans.
Proc Natl Acad Sci U S A
; 117(46): 28992-29000, 2020 11 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33139537
3.
A Phase 1, Randomized, Single-Ascending-Dose Study To Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S, an Anti-Staphylococcus aureus Thiomab Antibody-Antibiotic Conjugate, in Healthy Volunteers.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30910894
4.
A neutralizing anti-gH/gL monoclonal antibody is protective in the guinea pig model of congenital CMV infection.
PLoS Pathog
; 10(4): e1004060, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24722349
5.
A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors.
J Immunol
; 191(5): 2205-16, 2013 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23894201
6.
Semisynthetic model calibration for monitoring glucose in mammalian cell culture with in situ near infrared spectroscopy.
Biotechnol Bioeng
; 111(5): 896-903, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24284833
7.
Development of a safety biomarker signature to detect hepatic sinusoidal dilation associated with an anti-DLL4 biotherapeutic.
Biomarkers
; 19(5): 391-401, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24842386
8.
First-in-human phase 1 trial evaluating safety, pharmacokinetics, and pharmacodynamics of NLRP3 inflammasome inhibitor, GDC-2394, in healthy volunteers.
Clin Transl Sci
; 16(9): 1653-1666, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37350225
9.
A secreted protein microarray platform for extracellular protein interaction discovery.
Anal Biochem
; 420(2): 127-38, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21982860
10.
Peripheral blood gene expression predicts clinical benefit from anti-IL-13 in asthma.
J Allergy Clin Immunol
; 138(4): 1230-1233.e8, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27474124
11.
Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial.
Intensive Care Med
; 47(11): 1258-1270, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34609549
12.
Statistical techniques to construct assays for identifying likely responders to a treatment under evaluation from cell line genomic data.
BMC Cancer
; 10: 586, 2010 Oct 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-20979617
13.
Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment by bioluminescence imaging.
PLoS One
; 14(10): e0224096, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31661493
14.
Correlation of Cytomegalovirus (CMV) Disease Severity and Mortality With CMV Viral Burden in CMV-Seropositive Donor and CMV-Seronegative Solid Organ Transplant Recipients.
Open Forum Infect Dis
; 6(2): ofz003, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-30775403
15.
Sustained Circulating Bacterial Deoxyribonucleic Acid Is Associated With Complicated Staphylococcus aureus Bacteremia.
Open Forum Infect Dis
; 6(4): ofz090, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-31024970
16.
Balancing Efficacy and Safety of an Anti-DLL4 Antibody through Pharmacokinetic Modulation.
Clin Cancer Res
; 22(6): 1469-79, 2016 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26589434
17.
Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/ßKlotho Complex.
EBioMedicine
; 2(7): 730-43, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-26288846
18.
Protein microarrays for identification of novel extracellular protein-protein interactions.
Curr Protoc Protein Sci
; Chapter 27: Unit 27.3, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23546621
19.
PK-PD modeling of combination efficacy effect from administration of the MEK inhibitor GDC-0973 and PI3K inhibitor GDC-0941 in A2058 xenografts.
Cancer Chemother Pharmacol
; 71(1): 133-43, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23053270
20.
EGFR inhibitor erlotinib delays disease progression but does not extend survival in the SOD1 mouse model of ALS.
PLoS One
; 8(4): e62342, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23638043