Detalles de la búsqueda
1.
Survey of Pharmaceutical Industry's Best Practices around In Vitro Transporter Assessment and Implications for Drug Development: Considerations from the International Consortium for Innovation and Quality for Pharmaceutical Development Transporter Working Group.
Drug Metab Dispos
; 52(7): 582-596, 2024 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38697852
2.
Relevance of Human Aldoketoreductases and Microbial ß-Glucuronidases in Testosterone Disposition.
Drug Metab Dispos
; 51(4): 427-435, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36623880
3.
Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake of Glucuronide Metabolites of Androgens.
Mol Pharmacol
; 98(3): 234-242, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32587096
4.
Polybrominated Diphenyl Ethers and Gut Microbiome Modulate Metabolic Syndrome-Related Aqueous Metabolites in Mice.
Drug Metab Dispos
; 47(8): 928-940, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31123037
5.
PBDEs Altered Gut Microbiome and Bile Acid Homeostasis in Male C57BL/6 Mice.
Drug Metab Dispos
; 46(8): 1226-1240, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29769268
6.
Novel Interactions between Gut Microbiome and Host Drug-Processing Genes Modify the Hepatic Metabolism of the Environmental Chemicals Polybrominated Diphenyl Ethers.
Drug Metab Dispos
; 45(11): 1197-1214, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28864748
7.
Age-Specific Regulation of Drug-Processing Genes in Mouse Liver by Ligands of Xenobiotic-Sensing Transcription Factors.
Drug Metab Dispos
; 44(7): 1038-49, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-26577535
8.
Prediction of Hepatobiliary Clearances and Hepatic Concentrations of Transported Drugs in Humans Using Rosuvastatin as a Model Drug.
Clin Pharmacol Ther
; 112(3): 593-604, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35152400
9.
Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium.
Clin Pharmacol Ther
; 112(3): 461-484, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35390174
10.
Pitfalls in Predicting Hepatobiliary Drug Transport Using Human Sandwich-Cultured Hepatocytes.
AAPS J
; 22(5): 110, 2020 08 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32808154
11.
Transcriptomic profiling of PBDE-exposed HepaRG cells unveils critical lncRNA- PCG pairs involved in intermediary metabolism.
PLoS One
; 15(2): e0224644, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32101552
12.
Contribution of Uptake and Efflux Transporters to Oral Pharmacokinetics of Furosemide.
ACS Omega
; 5(51): 32939-32950, 2020 Dec 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-33403255
13.
Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.
J Steroid Biochem Mol Biol
; 191: 105350, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30959153
14.
Optimized Renal Transporter Quantification by Using Aquaporin 1 and Aquaporin 2 as Anatomical Markers: Application in Characterizing the Ontogeny of Renal Transporters and Its Correlation with Hepatic Transporters in Paired Human Samples.
AAPS J
; 21(5): 88, 2019 07 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31297641
15.
Regulation of protein-coding gene and long noncoding RNA pairs in liver of conventional and germ-free mice following oral PBDE exposure.
PLoS One
; 13(8): e0201387, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30067809
16.
Editor's Highlight: Neonatal Activation of the Xenobiotic-Sensors PXR and CAR Results in Acute and Persistent Down-regulation of PPARα-Signaling in Mouse Liver.
Toxicol Sci
; 153(2): 282-302, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27413110
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