Detalles de la búsqueda
1.
Harnessing polyhydroxylated pyrrolidines as a stabilizer of acid alpha-glucosidase (GAA) to enhance the efficacy of enzyme replacement therapy in Pompe disease.
Bioorg Med Chem
; 78: 117129, 2023 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36542959
2.
Synthesis of novel polyhydroxylated pyrrolidine-triazole/-isoxazole hybrid molecules.
Org Biomol Chem
; 13(7): 2100-7, 2015 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-25525831
3.
Mechanistic Insights into Dibasic Iminosugars as pH-Selective Pharmacological Chaperones to Stabilize Human α-Galactosidase.
JACS Au
; 4(3): 908-918, 2024 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38559739
4.
A practical synthesis of nitrone-derived C5a-functionalized isofagomines as protein stabilizers to treat Gaucher disease.
Commun Chem
; 7(1): 91, 2024 Apr 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38643239
5.
Discovery of small-molecule protein stabilizers toward exogenous alpha-l-iduronidase to reduce the accumulated heparan sulfate in mucopolysaccharidosis type I cells.
Eur J Med Chem
; 247: 115005, 2023 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36563498
6.
Synthesis of Nitrone-derived Pyrrolidine Scaffolds and Their Combinatorial Libraries to Develop Selective α-l-Rhamnosidase Inhibitors.
Chem Asian J
; 17(14): e202200172, 2022 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35535638
7.
Evolution of the complete photonic bandgap of two-dimensional photonic crystal.
Opt Express
; 19(6): 4862-7, 2011 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21445122
8.
Synthesis of (3S,4S,5S)-trihydroxylpiperidine derivatives as enzyme stabilizers to improve therapeutic enzyme activity in Fabry patient cell lines.
Eur J Med Chem
; 144: 626-634, 2018 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29289886
9.
A combinatorial approach towards the synthesis of non-hydrolysable triazole-iduronic acid hybrid inhibitors of human α-l-iduronidase: discovery of enzyme stabilizers for the potential treatment of MPSI.
Chem Commun (Camb)
; 54(21): 2647-2650, 2018 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29473068
10.
Rapid preparation of (3R,4S,5R) polyhydroxylated pyrrolidine-based libraries to discover a pharmacological chaperone for treatment of Fabry disease.
Eur J Med Chem
; 126: 1-6, 2017 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-27744182
11.
Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency.
Eur J Med Chem
; 123: 14-20, 2016 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27474919
Resultados
1 -
11
de 11
1
Próxima >
>>