Detalles de la búsqueda
1.
Growth of doxorubicin-resistant undifferentiated spindle-cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase.
J Cell Biochem
; 119(4): 3537-3544, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29143983
2.
Combination therapy of tumor-targeting Salmonella typhimurium A1-R and oral recombinant methioninase regresses a BRAF-V600E-negative melanoma.
Biochem Biophys Res Commun
; 503(4): 3086-3092, 2018 09 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-30166061
3.
Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model.
Chemotherapy
; 63(5): 278-283, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30673664
4.
Afterword: Oral Methioninase-Answer to Cancer and Fountain of Youth?
Methods Mol Biol
; 1866: 311-322, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30725426
5.
Safety and Toxicity of Recombinant Methioninase and Polyethylene Glycol (PEG) Recombinant Methioninase in Primates.
Methods Mol Biol
; 1866: 211-229, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30725418
6.
Pilot Phase I Clinical Trial of Methioninase on High-Stage Cancer Patients: Rapid Depletion of Circulating Methionine.
Methods Mol Biol
; 1866: 231-242, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30725419
7.
Efficacy of Recombinant Methioninase (rMETase) on Recalcitrant Cancer Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models: A Review.
Cells
; 8(5)2019 05 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31052611
8.
Development of Recombinant Methioninase for Cancer Treatment.
Methods Mol Biol
; 1866: 107-131, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30725412
9.
High Efficacy of Recombinant Methioninase on Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Cancer.
Methods Mol Biol
; 1866: 149-161, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30725414
10.
Human tumor growth in nude mice is associated with decreased plasma cysteine and homocysteine.
Anticancer Res
; 28(5A): 2541-4, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-19035276
11.
Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude mice.
Cancer Res
; 66(15): 7647-52, 2006 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16885365
12.
Targeting altered cancer methionine metabolism with recombinant methioninase (rMETase) overcomes partial gemcitabine-resistance and regresses a patient-derived orthotopic xenograft (PDOX) nude mouse model of pancreatic cancer.
Cell Cycle
; 17(7): 868-873, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29623758
13.
Recombinant methioninase (rMETase) is an effective therapeutic for BRAF-V600E-negative as well as -positive melanoma in patient-derived orthotopic xenograft (PDOX) mouse models.
Oncotarget
; 9(1): 915-923, 2018 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29416666
14.
Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer.
Cancer Lett
; 432: 251-259, 2018 09 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-29928962
15.
Intra-tumor L-methionine level highly correlates with tumor size in both pancreatic cancer and melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse models.
Oncotarget
; 9(13): 11119-11125, 2018 Feb 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-29541401
16.
Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention.
Cell Cycle
; 17(3): 356-361, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29187018
17.
Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma.
Cancer Lett
; 417: 168-173, 2018 03 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-29306021
18.
Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic.
Cell Cycle
; 17(6): 801-809, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29374999
19.
Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model.
Oncotarget
; 9(27): 19263-19272, 2018 Apr 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29721200
20.
Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice.
Oncotarget
; 8(33): 54616-54628, 2017 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28903369