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1.
Evaluation of a First PET Tracer Suitable for Imaging the Sigma-2 Receptor in the Brain of Nonhuman Primates.
Mol Pharm
; 21(1): 194-200, 2024 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38013422
2.
Presynaptic density determined by SV2A PET is closely associated with postsynaptic metabotropic glutamate receptor 5 availability and independent of amyloid pathology in early cognitive impairment.
Alzheimers Dement
; 20(6): 3876-3888, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38634334
3.
First-in-Human PET Imaging of [18F]SDM-4MP3: A Cautionary Tale.
Mol Imaging
; 2023: 8826977, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37719326
4.
Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET).
Eur J Nucl Med Mol Imaging
; 49(11): 3679-3691, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35633376
5.
Assessment of test-retest reproducibility of [18F]SynVesT-1, a novel radiotracer for PET imaging of synaptic vesicle glycoprotein 2A.
Eur J Nucl Med Mol Imaging
; 48(5): 1327-1338, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33416954
6.
Validation of SV2A-Targeted PET Imaging for Noninvasive Assessment of Neuroendocrine Differentiation in Prostate Cancer.
Int J Mol Sci
; 22(23)2021 Dec 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34884893
7.
Synthesis and in vivo evaluation of [18F]UCB-J for PET imaging of synaptic vesicle glycoprotein 2A (SV2A).
Eur J Nucl Med Mol Imaging
; 46(9): 1952-1965, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-31175396
8.
Novel Kappa Opioid Receptor Agonist as Improved PET Radiotracer: Development and in Vivo Evaluation.
Mol Pharm
; 16(4): 1523-1531, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30726092
9.
PET imaging of α7 nicotinic acetylcholine receptors: a comparative study of [18F]ASEM and [18F]DBT-10 in nonhuman primates, and further evaluation of [18F]ASEM in humans.
Eur J Nucl Med Mol Imaging
; 44(6): 1042-1050, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28120003
10.
Synthesis and evaluation of 1-phenyl-1H-1,2,3-triazole-4-carboxylic acid derivatives as xanthine oxidase inhibitors.
Bioorg Med Chem Lett
; 27(16): 3812-3816, 2017 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28693909
11.
Discovery and biological evaluation of some (1H-1,2,3-triazol-4-yl)methoxybenzaldehyde derivatives containing an anthraquinone moiety as potent xanthine oxidase inhibitors.
Bioorg Med Chem Lett
; 27(4): 729-732, 2017 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28131711
12.
PET imaging evaluation of [(18)F]DBT-10, a novel radioligand specific to α7 nicotinic acetylcholine receptors, in nonhuman primates.
Eur J Nucl Med Mol Imaging
; 43(3): 537-47, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26455500
13.
Imaging a putative marker of brain cortisol regulation in alcohol use disorder.
Neurobiol Stress
; 29: 100609, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38304303
14.
The associations between synaptic density and "A/T/N" biomarkers in Alzheimer's disease: An 18F-SynVesT-1 PET/MR study.
J Cereb Blood Flow Metab
; 44(7): 1199-1207, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38295871
15.
First-in-Human Study of 18F-SynVesT-2: An SV2A PET Imaging Probe with Fast Brain Kinetics and High Specific Binding.
J Nucl Med
; 2024 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38360052
16.
PET imaging of kappa opioid receptors and receptor expression quantified in neuron-derived extracellular vesicles in socially housed female and male cynomolgus macaques.
Neuropsychopharmacology
; 48(2): 410-417, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36100655
17.
Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q.
Sci Transl Med
; 14(647): eabi8593, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35648810
18.
Low-Dose Augmentation With Buprenorphine for Treatment-Resistant Depression: A Multisite Randomized Controlled Trial With Multimodal Assessment of Target Engagement.
Biol Psychiatry Glob Open Sci
; 2(2): 127-135, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36325158
19.
Further Investigation of Synaptic Vesicle Protein 2A (SV2A) Ligands Designed for Positron Emission Tomography and Single-Photon Emission Computed Tomography Imaging: Synthesis and Structure-Activity Relationship of Substituted Pyridinylmethyl-4-(3,5-difluorophenyl)pyrrolidin-2-ones.
ACS Omega
; 6(42): 27676-27683, 2021 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-34722967
20.
First-in-Human Evaluation of 18F-SynVesT-1, a Radioligand for PET Imaging of Synaptic Vesicle Glycoprotein 2A.
J Nucl Med
; 62(4): 561-567, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32859701