Detalles de la búsqueda
1.
Rational Design, Synthesis and Binding Affinity Studies of Anthraquinone Derivatives Conjugated to Gonadotropin-Releasing Hormone (GnRH) Analogues towards Selective Immunosuppression of Hormone-Dependent Cancer.
Int J Mol Sci
; 24(20)2023 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-37894912
2.
Synthesis, in vitro biological investigation, and molecular dynamics simulations of thiazolopyrimidine based compounds as corticotrophin releasing factor receptor-1 antagonists.
Bioorg Chem
; 114: 105079, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34174633
3.
Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP.
J Biol Chem
; 294(10): 3514-3531, 2019 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30622136
4.
Discovery of a stable tripeptide targeting the N-domain of CRF1 receptor.
Amino Acids
; 52(9): 1337-1351, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32996057
5.
Novel stable analogues of the neurotensin C-terminal hexapeptide containing unnatural amino acids.
Amino Acids
; 51(7): 1009-1022, 2019 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-31079216
6.
Host-Guest Interactions between Candesartan and Its Prodrug Candesartan Cilexetil in Complex with 2-Hydroxypropyl-ß-cyclodextrin: On the Biological Potency for Angiotensin II Antagonism.
Mol Pharm
; 16(3): 1255-1271, 2019 03 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30681344
7.
Effects of Cholesterol on GPCR Function: Insights from Computational and Experimental Studies.
Adv Exp Med Biol
; 1135: 89-103, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31098812
8.
Exploring new scaffolds for angiotensin II receptor antagonism.
Bioorg Med Chem
; 24(18): 4444-4451, 2016 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27480029
9.
Structural-functional analysis of the third transmembrane domain of the corticotropin-releasing factor type 1 receptor: role in activation and allosteric antagonism.
J Biol Chem
; 289(27): 18966-77, 2014 Jul 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-24838244
10.
Correction: Nonconventional glucagon and GLP-1 receptor agonist and antagonist interplay at the GLP-1 receptor revealed in high-throughput FRET assays for cAMP.
J Biol Chem
; 294(22): 8714, 2019 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-31152095
11.
GnRH-Gemcitabine conjugates for the treatment of androgen-independent prostate cancer: pharmacokinetic enhancements combined with targeted drug delivery.
Bioconjug Chem
; 25(4): 813-23, 2014 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-24661240
12.
Structural and Functional Insights into CRF Peptides and Their Receptors.
Biology (Basel)
; 13(2)2024 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38392338
13.
Corticotropin-releasing hormone deficiency results in impaired analgesic response during CFA-induced inflammation.
Hormones (Athens)
; 2024 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38740711
14.
Mapping structural determinants within third intracellular loop that direct signaling specificity of type 1 corticotropin-releasing hormone receptor.
J Biol Chem
; 287(12): 8974-85, 2012 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-22247544
15.
Design, synthesis, structural optimization, SAR, in silico prediction of physicochemical properties and pharmacological evaluation of novel & potent thiazolo[4,5-d]pyrimidine corticotropin releasing factor (CRF) receptor antagonists.
Eur J Pharm Sci
; 169: 106084, 2022 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34856350
16.
Evaluation of a stable gonadotropin-releasing hormone analog in mice for the treatment of endocrine disorders and prostate cancer.
J Pharmacol Exp Ther
; 336(3): 613-23, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-21106905
17.
Analgesic and Anti-Inflammatory Effects of the Synthetic Neurosteroid Analogue BNN27 during CFA-Induced Hyperalgesia.
Biomedicines
; 9(9)2021 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34572370
18.
Exploring the binding site crevice of a family B G protein-coupled receptor, the type 1 corticotropin releasing factor receptor.
Mol Pharmacol
; 78(4): 785-93, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20664003
19.
Alanine scanning mutagenesis of the second extracellular loop of type 1 corticotropin-releasing factor receptor revealed residues critical for peptide binding.
Mol Pharmacol
; 75(4): 793-800, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19124613
20.
Selective antagonism of CRF1 receptor by a substituted pyrimidine.
Hormones (Athens)
; 18(2): 215-221, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-30980254