Detalles de la búsqueda
1.
Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.
Biochemistry
; 60(48): 3714-3727, 2021 12 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34788017
2.
Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides.
Molecules
; 24(10)2019 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31096640
3.
Tuning the hybridization properties of modified oligonucleotides: from flexible to conformationally constrained phosphonate internucleotide linkages.
Org Biomol Chem
; 15(3): 701-707, 2017 Jan 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-27995239
4.
5'-O-Methylphosphonate nucleic acids--new modified DNAs that increase the Escherichia coli RNase H cleavage rate of hybrid duplexes.
Nucleic Acids Res
; 42(8): 5378-89, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24523351
5.
Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy.
Eur J Med Chem
; 259: 115685, 2023 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37567057
6.
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.
J Med Chem
; 65(20): 14082-14103, 2022 10 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36201304
7.
4'-Alkoxy oligodeoxynucleotides: a novel class of RNA mimics.
Org Biomol Chem
; 9(24): 8261-7, 2011 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-22051918
8.
Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine.
J Enzyme Inhib Med Chem
; 26(2): 155-61, 2011 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20578976
9.
Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.
Bioorg Med Chem Lett
; 20(3): 862-5, 2010 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20053558
10.
Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.
J Med Chem
; 62(23): 10676-10690, 2019 12 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31715099
11.
4-Toluenesulfonyloxymethyl-(H)-phosphinate: A Reagent for the Introduction of O- and S-Methyl-(H)-phosphinate Moieties.
Org Lett
; 18(11): 2704-7, 2016 06 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27177076
12.
Dr Jekyll and Mr Hyde: a strange case of 5-ethynyl-2'-deoxyuridine and 5-ethynyl-2'-deoxycytidine.
Open Biol
; 6(1): 150172, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26740587
13.
The Fingerprint of Anti-Bromodeoxyuridine Antibodies and Its Use for the Assessment of Their Affinity to 5-Bromo-2'-Deoxyuridine in Cellular DNA under Various Conditions.
PLoS One
; 10(7): e0132393, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26161977
14.
Straightforward Synthesis of Purine 4'-Alkoxy-2'-deoxynucleosides: First Report of Mixed Purine-Pyrimidine 4'-Alkoxyoligodeoxynucleotides as New RNA Mimics.
Org Lett
; 17(14): 3426-9, 2015 Jul 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-26133076
15.
Oligomerization aiming at phosphonate analogues of oligoadenylates.
Nucleosides Nucleotides Nucleic Acids
; 22(5-8): 1049-52, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14565341
16.
Inhibition of human thymidine phosphorylase by conformationally constrained pyrimidine nucleoside phosphonic acids and their "open-structure" isosteres.
Eur J Med Chem
; 74: 145-68, 2014 Mar 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-24462848
17.
Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity.
PLoS One
; 7(12): e51679, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23272138
18.
Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situ.
PLoS One
; 7(12): e52584, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23300711
19.
Hybridization properties of 4'-branched oligonucleotides.
Nucleosides Nucleotides Nucleic Acids
; 22(5-8): 1057-60, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14565343
20.
Prolinol-based nucleoside phosphonic acids: synthesis and properties.
Nucleic Acids Symp Ser (Oxf)
; (52): 537-8, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18776491