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1.
Pharmacokinetics and safety of sacubitril/valsartan (LCZ696) in patients with mild and moderate hepatic impairmentâ©.
Int J Clin Pharmacol Ther
; 55(9): 728-739, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28737127
2.
Osilodrostat (LCI699), a potent 11ß-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide: A 13-week study in rats.
Toxicol Appl Pharmacol
; 286(3): 224-33, 2015 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25981165
3.
Application of physiologically based absorption modeling to formulation development of a low solubility, low permeability weak base: mechanistic investigation of food effect.
AAPS PharmSciTech
; 15(2): 400-6, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24435225
4.
Utility of physiologically based modeling and preclinical in vitro/in vivo data to mitigate positive food effect in a BCS class 2 compound.
AAPS PharmSciTech
; 14(3): 1255-66, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23955148
5.
Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability.
Biopharm Drug Dispos
; 33(9): 536-49, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23097199
6.
Evaluation of Drug-Drug Interaction Potential Between Sacubitril/Valsartan (LCZ696) and Statins Using a Physiologically Based Pharmacokinetic Model.
J Pharm Sci
; 106(5): 1439-1451, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28089685
7.
9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers.
Cancer Lett
; 201(1): 17-24, 2003 Nov 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-14580682
8.
Case studies for practical food effect assessments across BCS/BDDCS class compounds using in silico, in vitro, and preclinical in vivo data.
AAPS J
; 15(1): 143-58, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23139017
9.
Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions.
Cancer Chemother Pharmacol
; 69(6): 1567-82, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22526410
10.
Unsymmetrical squaraines incorporating the thiophene unit for panchromatic dye-sensitized solar cells.
Org Lett
; 12(23): 5454-7, 2010 Dec 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-21047103
11.
Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi).
J Clin Pharmacol
; 50(4): 401-14, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19934029
12.
Effects of hepatic impairment on the pharmacokinetics of nilotinib: an open-label, single-dose, parallel-group study.
Clin Ther
; 31 Pt 2: 2459-69, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-20110053
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