Detalles de la búsqueda
1.
A common glycan structure on immunoglobulin G for enhancement of effector functions.
Proc Natl Acad Sci U S A
; 112(34): 10611-6, 2015 Aug 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26253764
2.
Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase.
Bioorg Med Chem Lett
; 25(5): 1117-23, 2015 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25630225
3.
Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer.
J Med Chem
; 66(4): 2566-2588, 2023 02 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-36749735
4.
Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
BMC Struct Biol
; 12: 32, 2012 Dec 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-23234314
5.
Design of potent bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase via targeted interactions with the active site 'capping' phenyls.
Bioorg Med Chem
; 20(18): 5583-91, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22884353
6.
Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
PLoS One
; 12(10): e0186447, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29036218
7.
Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design.
Eur J Med Chem
; 124: 186-199, 2016 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-27573544
8.
Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies.
Nat Chem
; 8(4): 338-46, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27001729
9.
Highly alpha-selective sialyl phosphate donors for efficient preparation of natural sialosides.
Chemistry
; 16(6): 1754-60, 2010 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-20066711
10.
Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate.
Acta Crystallogr F Struct Biol Commun
; 70(Pt 3): 299-304, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24598914
11.
Modular assembly of purine-like bisphosphonates as inhibitors of HIV-1 reverse transcriptase.
J Med Chem
; 57(17): 7435-49, 2014 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-25144111
12.
Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases.
J Med Chem
; 57(13): 5764-76, 2014 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24911527
13.
Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells.
J Med Chem
; 55(7): 3201-15, 2012 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-22390415
14.
Targeting the delivery of glycan-based paclitaxel prodrugs to cancer cells via glucose transporters.
J Med Chem
; 51(23): 7428-41, 2008 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-19053781
15.
Breast tumor microenvironment: proteomics highlights the treatments targeting secretome.
J Proteome Res
; 7(4): 1379-87, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18290608
Resultados
1 -
15
de 15
1
Próxima >
>>