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1.
Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes.
J Pharmacol Exp Ther
; 365(2): 262-271, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29440451
2.
Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor.
Xenobiotica
; 48(7): 647-655, 2018 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-28685622
3.
Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome.
Drug Metab Dispos
; 45(5): 501-511, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28254951
4.
Analyzing the changing trend of corneal biomechanical properties under different influencing factors in T2DM patients.
Sci Rep
; 14(1): 8160, 2024 04 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38589521
5.
Investigation of CYP3A induction by PF-05251749 in early clinical development: comparison of linear slope physiologically based pharmacokinetic prediction and biomarker response.
Clin Transl Sci
; 15(9): 2184-2194, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35730131
6.
Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.
Bioorg Med Chem Lett
; 21(9): 2725-31, 2011 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21183342
7.
The mediating effect of nurses' narrative ability on humanistic caring ability and humanistic caring behavior.
Asian J Surg
; 47(6): 2778-2779, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38388260
8.
Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia.
J Med Chem
; 51(1): 31-45, 2008 Jan 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-18072721
9.
Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors.
Bioorg Med Chem Lett
; 18(3): 1151-6, 2008 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18155906
10.
Poorer Prognosis of Primary Signet-Ring Cell Carcinoma of the Breast Compared with Mucinous Carcinoma.
PLoS One
; 11(9): e0162088, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27583684
11.
Effects and mechanism of recombinant human erythropoietin on the growth of human breast cancer MDA-MB-231 cells in nude mice.
Pathol Res Pract
; 211(8): 570-6, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26008780
12.
Multiple biomarkers of colorectal tumor in a differential diagnosis model: a quantitative study.
World J Gastroenterol
; 10(3): 439-42, 2004 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-14760775
13.
Evaluation of drugs with specific organ toxicities in organ-specific cell lines.
Toxicol Sci
; 126(1): 114-27, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22166485
14.
The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding.
J Lipid Res
; 50(3): 546-555, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18845619
15.
Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.
Bioorg Med Chem Lett
; 17(16): 4531-7, 2007 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17574411
16.
Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors.
Bioorg Med Chem Lett
; 17(16): 4538-44, 2007 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17574412
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