Detalles de la búsqueda
1.
Synthesis and biological evaluation of thieno[3,2-c]pyrazol-3-amine derivatives as potent glycogen synthase kinase 3ß inhibitors for Alzheimer's disease.
Bioorg Chem
; 138: 106663, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37329814
2.
Synthesis and anti-SARS-CoV-2 evaluation of lipid prodrugs of ß-D-N4-hydroxycytidine (NHC) and a 3'-fluoro-substituted analogue of NHC.
Bioorg Chem
; 135: 106527, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37031504
3.
Synthesis and biological evaluation of BU-4664L derivatives as potential anticancer agents.
Bioorg Med Chem Lett
; 55: 128474, 2022 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34838651
4.
Synthesis and biological evaluation of thieno[3,2-c]pyrazol-3-amine derivatives as potent glycogen synthase kinase 3ß inhibitors for Alzheimer's disease.
J Enzyme Inhib Med Chem
; 37(1): 1724-1736, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35698879
5.
Design, synthesis, and biological evaluation of 3-(1-benzotriazole)-nor-ß-lapachones as NQO1-directed antitumor agents.
Bioorg Chem
; 113: 104995, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34034133
6.
Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties.
Invest New Drugs
; 38(1): 29-38, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30887253
7.
Design, synthesis, bioevaluation of LFC- and PA-tethered anthraquinone analogues of mitoxantrone.
Bioorg Chem
; 101: 104005, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32599362
8.
Synthesis and Evaluation of Novel 2H-Benzo[e]-[1,2,4]thiadiazine 1,1-Dioxide Derivatives as PI3Kδ Inhibitors.
Molecules
; 24(23)2019 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-31775363
9.
Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity.
Molecules
; 24(2)2019 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30642134
10.
Design and synthesis of highly potent HIV-1 protease inhibitors with novel isosorbide-derived P2 ligands.
Bioorg Med Chem Lett
; 24(11): 2465-8, 2014 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24767846
11.
Synthesis of sulfonylhydrazone- and acylhydrazone-substituted 8-ethoxy-3-nitro-2H-chromenes as potent antiproliferative and apoptosis inducing agents.
Arch Pharm (Weinheim)
; 347(8): 576-88, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24866448
12.
Preparation of S14161 and its analogues and the discovery of 6-bromo-8-ethoxy-3-nitro-2H-chromene as a more potent antitumor agent in vitro.
Bioorg Med Chem Lett
; 23(11): 3314-9, 2013 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23601711
13.
Tumor selective self-assembled nanomicelles of carbohydrate-epothilone B conjugate for targeted chemotherapy.
Eur J Med Chem
; 259: 115693, 2023 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37531745
14.
Recent Advances in Dual BRD4-Kinase Inhibitors Based on Polypharmacology.
ChemMedChem
; 17(6): e202100731, 2022 03 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-35146935
15.
A branched small molecule-drug conjugate nanomedicine strategy for the targeted HCC chemotherapy.
Eur J Med Chem
; 228: 114037, 2022 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34883290
16.
Synthesis and evaluation of trehalose-based compounds as anti-invasive agents.
Bioorg Med Chem Lett
; 21(4): 1089-91, 2011 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21269828
17.
Design and synthesis of potent HIV-1 protease inhibitors incorporating hydroxyprolinamides as novel P2 ligands.
Bioorg Med Chem Lett
; 21(12): 3730-3, 2011 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21555220
18.
Recent developments of RET protein kinase inhibitors with diverse scaffolds as hinge binders.
Future Med Chem
; 13(1): 45-62, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33242992
19.
Recent Advances in the Development of Casein Kinase 1 Inhibitors.
Curr Med Chem
; 28(8): 1585-1604, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-32660395
20.
Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease.
Eur J Med Chem
; 225: 113821, 2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34517222