Detalles de la búsqueda
1.
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.
Nature
; 605(7911): 741-746, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35508656
2.
The effect of aspirin and eicosapentaenoic acid on urinary biomarkers of prostaglandin E2 synthesis and platelet activation in participants of the seAFOod polyp prevention trial.
Int J Cancer
; 154(5): 873-885, 2024 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37855394
3.
Cytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin Agents.
Drug Metab Dispos
; 50(1): 49-57, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34607808
4.
Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the Ileal Microbiome, in Humans with a Temporary Ileostomy.
J Nutr
; 151(8): 2142-2152, 2021 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34036331
5.
Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds.
Bioorg Med Chem
; 40: 116167, 2021 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33932713
6.
Targeted microbubbles carrying lipid-oil-nanodroplets for ultrasound-triggered delivery of the hydrophobic drug, combretastatin A4.
Nanomedicine
; 36: 102401, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33894396
7.
An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors.
Analyst
; 145(13): 4512-4521, 2020 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32412559
8.
Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2â×â2 factorial trial.
Lancet
; 392(10164): 2583-2594, 2018 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30466866
9.
A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota.
Gut
; 67(11): 1974-1983, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28951525
10.
An optimised assay for quantitative, high-throughput analysis of polysialyltransferase activity.
Analyst
; 141(20): 5849-5856, 2016 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-27517096
11.
Thin-layer chromatography/matrix-assisted laser desorption/ionisation mass spectrometry and matrix-assisted laser desorption/ionisation mass spectrometry imaging for the analysis of phospholipids in LS174T colorectal adenocarcinoma xenografts treated with the vascular disrupting agent DMXAA.
Rapid Commun Mass Spectrom
; 29(14): 1288-96, 2015 Jul 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-26405790
12.
Anticolorectal cancer activity of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid.
Gut
; 63(11): 1760-8, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24470281
13.
Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis-associated colorectal cancer acting on Notch signaling and gut microbiota.
Int J Cancer
; 135(9): 2004-13, 2014 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24676631
14.
Development of novel tumor-targeted theranostic nanoparticles activated by membrane-type matrix metalloproteinases for combined cancer magnetic resonance imaging and therapy.
Small
; 10(3): 566-75, 417, 2014 Feb 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-24038954
15.
Tumor-targeted prodrug ICT2588 demonstrates therapeutic activity against solid tumors and reduced potential for cardiovascular toxicity.
Mol Pharm
; 11(4): 1294-300, 2014 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24641451
16.
Maleimide-Thiol Linkages Alter the Biodistribution of SN38 Therapeutic Microbubbles Compared to Biotin-Avidin While Preserving Parity in Tumoral Drug Delivery.
Pharmaceutics
; 16(3)2024 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38543328
17.
APOE genotype, eicosapentaenoic acid (EPA) supplementation and n-3 highly unsaturated fatty acid (HUFA) levels in patients with multiple colorectal polyps: A secondary analysis of the seAFOod polyp prevention trial.
Prostaglandins Leukot Essent Fatty Acids
; 201: 102623, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38823349
18.
Cancer-specific glycosylation of CD13 impacts its detection and activity in preclinical cancer tissues.
iScience
; 26(11): 108219, 2023 Nov 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37942010
19.
Colorectal polyp outcomes after participation in the seAFOod polyp prevention trial: Evidence of rebound elevated colorectal polyp risk after short-term aspirin use.
Aliment Pharmacol Ther
; 58(6): 562-572, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37518954
20.
Polymorphisms in Cyclooxygenase, Lipoxygenase, and TP53 Genes Predict Colorectal Polyp Risk Reduction by Aspirin in the seAFOod Polyp Prevention Trial.
Cancer Prev Res (Phila)
; 16(11): 621-629, 2023 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37756582