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1.
CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML).
Cancer Cell
; 1(5): 421-32, 2002 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-12124172
2.
Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.
Cancer Res
; 62(13): 3729-35, 2002 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12097282
3.
PDGF C is a selective alpha platelet-derived growth factor receptor agonist that is highly expressed in platelet alpha granules and vascular smooth muscle.
Arterioscler Thromb Vasc Biol
; 24(4): 787-92, 2004 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15061151
4.
Potent and selective inhibitors of PDGF receptor phosphorylation. 2. Synthesis, structure activity relationship, improvement of aqueous solubility, and biological effects of 4-[4-(N-substituted (thio)carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazoline derivatives.
J Med Chem
; 45(20): 4513-23, 2002 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-12238930
5.
Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 1. Synthesis, structure-activity relationship, and biological effects of a new class of quinazoline derivatives.
J Med Chem
; 45(14): 3057-66, 2002 Jul 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-12086491
6.
A double-blind, randomised, placebo-controlled, phase 2b study evaluating sorafenib in combination with paclitaxel as a first-line therapy in patients with HER2-negative advanced breast cancer.
Eur J Cancer
; 49(2): 312-22, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22954665
7.
Sorafenib or placebo with either gemcitabine or capecitabine in patients with HER-2-negative advanced breast cancer that progressed during or after bevacizumab.
Clin Cancer Res
; 19(10): 2745-54, 2013 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23444220
8.
Sorafenib in combination with oxaliplatin, leucovorin, and fluorouracil (modified FOLFOX6) as first-line treatment of metastatic colorectal cancer: the RESPECT trial.
Clin Cancer Res
; 19(9): 2541-50, 2013 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23532888
9.
Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518.
Blood
; 104(9): 2867-72, 2004 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15256420
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