Detalles de la búsqueda
1.
Na+ controls hypoxic signalling by the mitochondrial respiratory chain.
Nature
; 586(7828): 287-291, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32728214
2.
Innovative pathological network-based multitarget approaches for Alzheimer's disease treatment.
Med Res Rev
; 2024 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38678582
3.
Reduction in Hippocampal Amyloid-ß Peptide (Aß) Content during Glycine-Proline-Glutamate (Gly-Pro-Glu) Co-Administration Is Associated with Changes in Inflammation and Insulin-like Growth Factor (IGF)-I Signaling.
Int J Mol Sci
; 25(11)2024 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38891902
4.
KEAP1-NRF2 protein-protein interaction inhibitors: Design, pharmacological properties and therapeutic potential.
Med Res Rev
; 43(1): 237-287, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36086898
5.
From single drug targets to synergistic network pharmacology in ischemic stroke.
Proc Natl Acad Sci U S A
; 116(14): 7129-7136, 2019 04 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30894481
6.
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach.
Pharmacol Rev
; 70(2): 348-383, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29507103
7.
Central Activation of Alpha7 Nicotinic Signaling Attenuates LPS-Induced Neuroinflammation and Sickness Behavior in Adult but Not in Aged Animals.
Molecules
; 26(8)2021 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33916910
8.
Melatonin-sulforaphane hybrid ITH12674 attenuates glial response in vivo by blocking LPS binding to MD2 and receptor oligomerization.
Pharmacol Res
; 152: 104597, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31838078
9.
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.
Proc Natl Acad Sci U S A
; 114(46): 12315-12320, 2017 11 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-29087944
10.
Protective Effects of Ursolic Acid Against Cytotoxicity Induced by Corticosterone: Role of Protein Kinases.
Neurochem Res
; 2019 Nov 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31713091
11.
Pharmacological doses of melatonin impede cognitive decline in tau-related Alzheimer models, once tauopathy is initiated, by restoring the autophagic flux.
J Pineal Res
; 67(1): e12578, 2019 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-30943316
12.
Chromaffin cells as a model to evaluate mechanisms of cell death and neuroprotective compounds.
Pflugers Arch
; 470(1): 187-198, 2018 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28823085
13.
The APPswe/PS1A246E mutations in an astrocytic cell line leads to increased vulnerability to oxygen and glucose deprivation, Ca2+ dysregulation, and mitochondrial abnormalities.
J Neurochem
; 145(2): 170-182, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29315575
14.
Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca(2+) release from the endoplasmic reticulum.
J Neurochem
; 133(3): 309-19, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25650007
15.
The modulation of NMDA receptors and L-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test.
Amino Acids
; 47(4): 795-811, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25555469
16.
Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate.
Biochim Biophys Acta
; 1832(6): 705-17, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23415811
17.
Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression.
J Pineal Res
; 56(2): 204-12, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24350834
18.
Adipose tissue as a therapeutic target for vascular damage in Alzheimer's disease.
Br J Pharmacol
; 181(6): 840-878, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-37706346
19.
Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions.
J Neurochem
; 126(4): 437-50, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23713463
20.
Cytotoxicity Models in Chromaffin Cells to Evaluate Neuroprotective Compounds.
Methods Mol Biol
; 2565: 361-370, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36205906