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1.
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
Bioorg Med Chem
; 22(18): 5097-109, 2014 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24398384
2.
Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation.
Bioorg Med Chem Lett
; 20(9): 2733-9, 2010 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20378350
3.
alpha-halogenoacrylic derivatives of antitumor agents.
Mini Rev Med Chem
; 9(1): 81-94, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19149662
4.
Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymerization.
Bioorg Med Chem
; 16(18): 8419-26, 2008 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18755591
5.
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
J Med Chem
; 50(9): 2273-7, 2007 May 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-17419607
6.
Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation.
Eur J Med Chem
; 108: 39-52, 2016 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26629859
7.
Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study.
Eur J Med Chem
; 101: 185-204, 2015 Aug 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26141910
8.
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.
J Med Chem
; 58(7): 3209-22, 2015 Apr 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-25785605
9.
Synthesis and biological effects of novel 2-amino-3-(4-chlorobenzoyl)-4-substituted thiophenes as allosteric enhancers of the A1 adenosine receptor.
Eur J Med Chem
; 67: 409-27, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23911855
10.
Concise synthesis and biological evaluation of 2-Aroyl-5-amino benzo[b]thiophene derivatives as a novel class of potent antimitotic agents.
J Med Chem
; 56(22): 9296-309, 2013 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24164557
11.
Synthesis and antitumor molecular mechanism of agents based on amino 2-(3',4',5'-trimethoxybenzoyl)benzo[b]furan: inhibition of tubulin and induction of apoptosis.
ChemMedChem
; 6(10): 1841-53, 2011 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-21805646
12.
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazole: a unique, highly active antimicrotubule agent.
Eur J Med Chem
; 46(12): 6015-24, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22027100
13.
Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.
J Med Chem
; 53(10): 4248-58, 2010 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-20420439
14.
The P2X7 receptor as a therapeutic target.
Expert Opin Ther Targets
; 12(5): 647-61, 2008 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-18410246
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