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1.
A novel class of oxazepine-based anti-cancer agents induces cell death in primary human CLL cells and efficiently reduces tumor growth in Eµ-TCL1 mice through the JNK/STAT4/p66Shc axis.
Pharmacol Res
; 174: 105965, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34732370
2.
Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS).
Molecules
; 24(8)2019 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-31027295
3.
p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation.
Front Cell Dev Biol
; 12: 1297116, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38389706
4.
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients.
Biomed Pharmacother
; 174: 116537, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38579402
5.
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia.
Cell Death Dis
; 15(2): 144, 2024 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38360867
6.
p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB.
Front Oncol
; 12: 877495, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35847884
7.
Evidence of Destabilization of the Human Thymidylate Synthase (hTS) Dimeric Structure Induced by the Interface Mutation Q62R.
Biomolecules
; 9(4)2019 04 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30987202
8.
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents.
Eur J Med Chem
; 162: 290-320, 2019 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30448418
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