Detalles de la búsqueda
1.
Generality of Enhancing the Dissolution Rates of Free Acid Amorphous Solid Dispersions by the Incorporation of Sodium Hydroxide.
Mol Pharm
; 21(7): 3395-3406, 2024 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38836777
2.
Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing.
Mol Pharm
; 21(2): 564-580, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38215042
3.
Development of an Amorphous Solid Dispersion Formulation for Mitigating Mechanical Instability of Crystalline Form and Improving Bioavailability for Early Phase Clinical Studies.
Mol Pharm
; 20(5): 2452-2464, 2023 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37010134
4.
Magic angle spinning dynamic nuclear polarization solid-state NMR spectroscopy of γ-irradiated molecular organic solids.
Solid State Nucl Magn Reson
; 119: 101785, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35405629
5.
Effect of Counterions on Dissolution of Amorphous Solid Dispersions Studied by Surface Area Normalized Dissolution.
Mol Pharm
; 18(9): 3429-3438, 2021 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34338529
6.
Optimization of Spray-Drying Parameters for Formulation Development at Preclinical Scale.
AAPS PharmSciTech
; 23(1): 28, 2021 Dec 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-34931259
7.
Fast Acquisition of Proton-Detected HETCOR Solid-State NMR Spectra of Quadrupolar Nuclei and Rapid Measurement of NH Bond Lengths by Frequency Selective HMQC and RESPDOR Pulse Sequences.
Chemistry
; 26(35): 7881-7888, 2020 Jun 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32315472
8.
Rapid Characterization of Formulated Pharmaceuticals Using Fast MAS 1H Solid-State NMR Spectroscopy.
Mol Pharm
; 16(7): 3121-3132, 2019 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31095913
9.
Correction to "Inhaled JAK Inhibitor GDC-0214 Nanoaggregate Powder Exhibits Improved Pharmacokinetic Profile in Rats Compared to the Micronized Form: Benefits of Thin Film Freezing".
Mol Pharm
; 21(6): 3077, 2024 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38663036
10.
In Situ Salt Formation during Melt Extrusion for Improved Chemical Stability and Dissolution Performance of a Meloxicam-Copovidone Amorphous Solid Dispersion.
Mol Pharm
; 15(3): 1226-1237, 2018 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29412681
11.
Understanding Phase Behavior of Nearly Energetically Equivalent Polymorphs To Achieve Controlled Crystallization for a Nav1.7 Pain Inhibitor Compound.
Mol Pharm
; 15(11): 5072-5080, 2018 11 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30216726
12.
In Vitro, in Silico, and in Vivo Assessments of Intestinal Precipitation and Its Impact on Bioavailability of a BCS Class 2 Basic Compound.
Mol Pharm
; 15(4): 1607-1617, 2018 04 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29522347
13.
Solid-State NMR Investigation of Drug-Excipient Interactions and Phase Behavior in Indomethacin-Eudragit E Amorphous Solid Dispersions.
Pharm Res
; 35(3): 65, 2018 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29464409
14.
Exploring Molecular Speciation and Crystallization Mechanism of Amorphous 2-Phenylamino Nicotinic Acid.
Pharm Res
; 35(3): 51, 2018 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29417314
15.
Characterization of the Particle Size and Polydispersity of Dicumarol Using Solid-State NMR Spectroscopy.
Mol Pharm
; 14(3): 856-865, 2017 03 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28166408
16.
Impact of Supramolecular Aggregation on the Crystallization Kinetics of Organic Compounds from the Supercooled Liquid State.
Mol Pharm
; 14(6): 2126-2137, 2017 06 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28485947
17.
Enhancing the resolution of 1H and 13C solid-state NMR spectra by reduction of anisotropic bulk magnetic susceptibility broadening.
Phys Chem Chem Phys
; 19(41): 28153-28162, 2017 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29022618
18.
Acid-Base Interactions of Polystyrene Sulfonic Acid in Amorphous Solid Dispersions Using a Combined UV/FTIR/XPS/ssNMR Study.
Mol Pharm
; 13(2): 483-92, 2016 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26716395
19.
Probing the Distribution of Water in a Multi-Component System by Solid-State NMR Spectroscopy.
Pharm Res
; 33(10): 2470-80, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27324960
20.
Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability.
Bioorg Med Chem Lett
; 26(2): 575-579, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26675441