Detalles de la búsqueda
1.
Pharmacokinetics and Safety of Lurbinectedin Administrated with Itraconazole in Cancer Patients: A Drug-Drug Interaction Study.
Mar Drugs
; 22(4)2024 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38667795
2.
Limited sampling strategies for tacrolimus exposure (AUC0-24) prediction after Prograf(®) and Advagraf(®) administration in children and adolescents with liver or kidney transplants.
Transpl Int
; 27(9): 939-48, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24861353
3.
Impact of a Moderate CYP3A4 Inducer (Bosentan) on Lurbinectedin Pharmacokinetics and Safety in Patients with Advanced Solid Tumors: An Open-Label, Two-Way, Crossover, Phase Ib Drug-Drug Interaction Study.
Pharmaceuticals (Basel)
; 17(2)2024 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38399397
4.
Contribution of genetic background, traditional risk factors, and HIV-related factors to coronary artery disease events in HIV-positive persons.
Clin Infect Dis
; 57(1): 112-21, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23532479
5.
Contribution of CYP2B6 alleles in explaining extreme (S)-methadone plasma levels: a CYP2B6 gene resequencing study.
Pharmacogenet Genomics
; 23(2): 84-93, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23249875
6.
Pharmacogenetics-based population pharmacokinetic analysis of etravirine in HIV-1 infected individuals.
Pharmacogenet Genomics
; 23(1): 9-18, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23111422
7.
Phase 1 study of two inodilators in neonates undergoing cardiovascular surgery.
Pediatr Res
; 73(1): 95-103, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23138399
8.
A model-based head-to-head comparison of single-agent lurbinectedin in the pivotal ATLANTIS Study.
Front Oncol
; 13: 1152371, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37397388
9.
Quantitative determination of lurbinectedin, its unbound fraction and its metabolites in human plasma utilizing ultra-performance LC-MS/MS.
PLoS One
; 18(3): e0283783, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36996147
10.
Population pharmacokinetic analysis and pharmacogenetics of raltegravir in HIV-positive and healthy individuals.
Antimicrob Agents Chemother
; 56(6): 2959-66, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22371894
11.
Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study.
J Infect Dis
; 203(2): 246-57, 2011 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21288825
12.
Integrated exposure-response analysis of efficacy and safety of lurbinectedin to support the dose regimen in small-cell lung cancer.
Cancer Chemother Pharmacol
; 89(5): 585-594, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34739582
13.
Anti-cancer drug combinations approved by US FDA from 2011 to 2021: main design features of clinical trials and role of pharmacokinetics.
Cancer Chemother Pharmacol
; 90(4): 285-299, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36029310
14.
Preclinical and randomized phase I studies of plitidepsin in adults hospitalized with COVID-19.
Life Sci Alliance
; 5(4)2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35012962
15.
Population Pharmacokinetic-Pharmacodynamic Modeling and Covariate Analyses of Neutropenia and Thrombocytopenia in Patients With Solid Tumors Treated With Lurbinectedin.
J Clin Pharmacol
; 61(9): 1206-1219, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33914350
16.
Effect of lurbinectedin on the QTc interval in patients with advanced solid tumors: an exposure-response analysis.
Cancer Chemother Pharmacol
; 87(1): 113-124, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33108504
17.
Plitidepsin has a positive therapeutic index in adult patients with COVID-19 requiring hospitalization.
medRxiv
; 2021 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-34075384
18.
ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir.
Pharmacogenet Genomics
; 20(4): 217-30, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20139798
19.
Genetic polymorphisms of CYP1A2, CYP3A4, CYP3A5, pregnane/steroid X receptor and constitutive androstane receptor in 207 healthy Spanish volunteers.
Clin Chem Lab Med
; 48(5): 635-9, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20218903
20.
Population-Pharmacokinetic and Covariate Analysis of Lurbinectedin (PM01183), a New RNA Polymerase II Inhibitor, in Pooled Phase I/II Trials in Patients with Cancer.
Clin Pharmacokinet
; 58(3): 363-374, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30090974