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1.
A Pharmacokinetic and Metabolism Study of the TRPC6 Inhibitor SH045 in Mice by LC-MS/MS.
Int J Mol Sci
; 23(7)2022 Mar 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-35408998
2.
Improved in vivo PET imaging of the adenosine A2A receptor in the brain using [18F]FLUDA, a deuterated radiotracer with high metabolic stability.
Eur J Nucl Med Mol Imaging
; 48(9): 2727-2736, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33532910
3.
(+)-[18F]Flubatine as a novel α4ß2 nicotinic acetylcholine receptor PET ligand-results of the first-in-human brain imaging application in patients with ß-amyloid PET-confirmed Alzheimer's disease and healthy controls.
Eur J Nucl Med Mol Imaging
; 48(3): 731-746, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32935187
4.
In vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain.
Bioorg Med Chem Lett
; 48: 128254, 2021 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34256118
5.
Development of fluorinated and methoxylated benzothiazole derivatives as highly potent and selective cannabinoid CB2 receptor ligands.
Bioorg Chem
; 114: 105191, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34375194
6.
Development of 18F-Labeled Radiotracers for PET Imaging of the Adenosine A2A Receptor: Synthesis, Radiolabeling and Preliminary Biological Evaluation.
Int J Mol Sci
; 22(5)2021 Feb 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-33669003
7.
Design, Radiosynthesis and Preliminary Biological Evaluation in Mice of a Brain-Penetrant 18F-Labelled σ2 Receptor Ligand.
Int J Mol Sci
; 22(11)2021 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-34064122
8.
Preclinical Evaluation of [18F]FACH in Healthy Mice and Piglets: An 18F-Labeled Ligand for Imaging of Monocarboxylate Transporters with PET.
Int J Mol Sci
; 22(4)2021 Feb 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33562048
9.
Preclinical Incorporation Dosimetry of [18F]FACH-A Novel 18F-Labeled MCT1/MCT4 Lactate Transporter Inhibitor for Imaging Cancer Metabolism with PET.
Molecules
; 25(9)2020 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-32357571
10.
Sigma-1 Receptor Positron Emission Tomography: A New Molecular Imaging Approach Using (S)-(-)-[18F]Fluspidine in Glioblastoma.
Molecules
; 25(9)2020 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32384802
11.
Development of Novel Analogs of the Monocarboxylate Transporter Ligand FACH and Biological Validation of One Potential Radiotracer for Positron Emission Tomography (PET) Imaging.
Molecules
; 25(10)2020 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32423056
12.
Targeting cyclic nucleotide phosphodiesterase 5 (PDE5) in brain: Toward the development of a PET radioligand labeled with fluorine-18.
Bioorg Chem
; 86: 346-362, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30753989
13.
Development and radiosynthesis of the first 18 F-labeled inhibitor of monocarboxylate transporters (MCTs).
J Labelled Comp Radiopharm
; 62(8): 411-424, 2019 06 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-31017677
14.
Synthesis and In Vitro Evaluation of 8-Pyridinyl-Substituted Benzo[e]imidazo[2,1-c][1,2,4]triazines as Phosphodiesterase 2A Inhibitors.
Molecules
; 24(15)2019 Jul 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-31370274
15.
Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine- Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography.
Molecules
; 24(22)2019 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31731831
16.
Exploring the Metabolism of (+)-[18F]Flubatine in Vitro and in Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study.
Molecules
; 23(2)2018 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29461507
17.
LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand for Imaging α4ß2 Nicotinic Acetylcholine Receptors.
Molecules
; 21(9)2016 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27617996
18.
[18F]Fluspidine-A PET Tracer for Imaging of σ1 Receptors in the Central Nervous System.
Pharmaceuticals (Basel)
; 17(2)2024 Jan 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38399380
19.
Preclinical evaluation of an 18F-labeled Nε-acryloyllysine piperazide for covalent targeting of transglutaminase 2.
EJNMMI Radiopharm Chem
; 9(1): 1, 2024 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38165538
20.
Development of the High-Affinity Carborane-Based Cannabinoid Receptor Type 2 PET Ligand [18F]LUZ5-d8.
J Med Chem
; 66(7): 5242-5260, 2023 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36944112