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1.
Biomarkers and clinical outcomes after tezepelumab cessation: Extended follow-up from the 2-year DESTINATION study.
Ann Allergy Asthma Immunol
; 2024 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38697286
2.
Physiologically Based Pharmacokinetic Model of Itraconazole and Two of Its Metabolites to Improve the Predictions and the Mechanistic Understanding of CYP3A4 Drug-Drug Interactions.
Drug Metab Dispos
; 46(10): 1420-1433, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30068519
3.
High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile.
Xenobiotica
; 44(6): 498-510, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24320817
4.
Understanding Statin-Roxadustat Drug-Drug-Disease Interaction Using Physiologically-Based Pharmacokinetic Modeling.
Clin Pharmacol Ther
; 114(4): 825-835, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37376792
5.
Does the choice of applied physiologically-based pharmacokinetics platform matter? A case study on simvastatin disposition and drug-drug interaction.
CPT Pharmacometrics Syst Pharmacol
; 11(9): 1194-1209, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35722750
6.
In vivo investigation in pigs of intestinal absorption, hepatobiliary disposition, and metabolism of the 5α-reductase inhibitor finasteride and the effects of coadministered ketoconazole.
Drug Metab Dispos
; 39(5): 847-57, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21317368
7.
Effects of ketoconazole on the in vivo biotransformation and hepatobiliary transport of the thrombin inhibitor AZD0837 in pigs.
Drug Metab Dispos
; 39(2): 239-46, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-20978106
8.
Model-Based Analysis Reveals a Sustained and Dose-Dependent Acceleration of Wound Healing by VEGF-A mRNA (AZD8601).
CPT Pharmacometrics Syst Pharmacol
; 9(7): 384-394, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32438492
9.
Identification of finasteride metabolites in human bile and urine by high-performance liquid chromatography/tandem mass spectrometry.
Drug Metab Dispos
; 37(10): 2008-17, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19635781
10.
Enterohepatic disposition of rosuvastatin in pigs and the impact of concomitant dosing with cyclosporine and gemfibrozil.
Drug Metab Dispos
; 37(12): 2349-58, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19773540
11.
Human hepatocytes and cytochrome P450-selective inhibitors predict variability in human drug exposure more accurately than human recombinant P450s.
Br J Pharmacol
; 175(11): 2116-2129, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29574682
12.
Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing.
Sci Rep
; 8(1): 17509, 2018 11 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-30504800
13.
Drug metabolism of CYP3A4, CYP2C9 and CYP2D6 substrates in pigs and humans.
Eur J Pharm Sci
; 43(3): 89-98, 2011 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21447389
14.
The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men.
Eur J Pharm Sci
; 36(4-5): 433-43, 2009 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-19073252
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