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1.
Influence of Glutathione-S-Transferase A1*B Allele on the Metabolism of the Aromatase Inhibitor, Exemestane, in Human Liver Cytosols and in Patients Treated With Exemestane.
J Pharmacol Exp Ther
; 382(3): 327-334, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35793834
2.
Variation in the UGT2B17 genotype, exemestane metabolism and menopause-related toxicities in the CCTG MAP.3 trial.
Breast Cancer Res Treat
; 183(3): 705-716, 2020 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-32715442
3.
Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17ß12 as the reductase important in (R)-NNAL formation in human lung.
Carcinogenesis
; 39(8): 1079-1088, 2018 07 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-29788210
4.
Identification and Quantification of Novel Major Metabolites of the Steroidal Aromatase Inhibitor, Exemestane.
Drug Metab Dispos
; 46(12): 1867-1878, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30257855
5.
A 3D QSAR study of betulinic acid derivatives as anti-tumor agents using topomer CoMFA: model building studies and experimental verification.
Molecules
; 18(9): 10228-41, 2013 Aug 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-23973995
6.
Patient-derived microphysiological model identifies the therapeutic potential of metformin for thoracic aortic aneurysm.
EBioMedicine
; 81: 104080, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35636318
7.
Aorta smooth muscle-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease.
Elife
; 102021 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34486519
8.
Phase II metabolism of betulin by rat and human UDP-glucuronosyltransferases and sulfotransferases.
Chem Biol Interact
; 302: 190-195, 2019 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30776358
9.
Association between Glucuronidation Genotypes and Urinary NNAL Metabolic Phenotypes in Smokers.
Cancer Epidemiol Biomarkers Prev
; 25(7): 1175-1184, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-27197298
10.
Pharmacokinetic analysis and comparison of caffeine administered rapidly or slowly in coffee chilled or hot versus chilled energy drink in healthy young adults.
Clin Toxicol (Phila)
; 54(4): 308-12, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27100333
11.
Proteomic investigation into betulinic acid-induced apoptosis of human cervical cancer HeLa cells.
PLoS One
; 9(8): e105768, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25148076
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