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1.
Discovery of thiazole salt AChE inhibitors and development of thiamine disulfide prodrugs targeting the central nervous system.
Bioorg Chem
; 139: 106702, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37390634
2.
Discovery of potent glycogen synthase kinase 3/cholinesterase inhibitors with neuroprotection as potential therapeutic agent for Alzheimer's disease.
Bioorg Med Chem
; 30: 115940, 2021 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33340937
3.
Anti-cancer adjuvant drug screening via epithelial-mesenchymal transition-related aptamer probe.
Anal Bioanal Chem
; 413(28): 6951-6962, 2021 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-34676432
4.
Computational design of binder as the LC3-p62 protein-protein interaction.
Bioorg Chem
; 115: 105241, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34426157
5.
Targeting glycogen synthase kinase-3ß for Alzheimer's disease: Recent advances and future Prospects.
Eur J Med Chem
; 265: 116065, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38160617
6.
Opportunities and perspectives of small molecular phosphodiesterase inhibitors in neurodegenerative diseases.
Eur J Med Chem
; 271: 116386, 2024 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38614063
7.
Discovery of 4-benzylpiperazinequinoline BChE inhibitor that suppresses neuroinflammation for the treatment of Alzheimer's disease.
Eur J Med Chem
; 272: 116463, 2024 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38704944
8.
Discovery of NLRP3 inhibitors using machine learning: Identification of a hit compound to treat NLRP3 activation-driven diseases.
Eur J Med Chem
; 260: 115784, 2023 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37672931
9.
Discovery of Resorcinol-Based Polycyclic Structures as Tyrosinase Inhibitors for Treatment of Parkinson's Disease.
ACS Chem Neurosci
; 13(1): 81-96, 2022 01 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34882402
10.
A highly effective and stable butyrylcholinesterase inhibitor with multi-faceted neuroprotection and cognition improvement.
Eur J Med Chem
; 239: 114510, 2022 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35728508
11.
Design, synthesis and evaluation of fused hybrids with acetylcholinesterase inhibiting and Nrf2 activating functions for Alzheimer's disease.
Eur J Med Chem
; 244: 114806, 2022 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36223681
12.
Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance.
ACS Med Chem Lett
; 13(8): 1286-1294, 2022 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-35978698
13.
N-Benzyl Benzamide Derivatives as Selective Sub-Nanomolar Butyrylcholinesterase Inhibitors for Possible Treatment in Advanced Alzheimer's Disease.
J Med Chem
; 65(16): 11365-11387, 2022 08 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35969197
14.
In silico approaches using pharmacophore model combined with molecular docking for discovery of novel ULK1 inhibitors.
Future Med Chem
; 13(4): 341-361, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33427493
15.
Discovery of 2-(cyclopropanecarboxamido)-N-(5-((1-(4-fluorobenzyl)piperidin-4-yl)methoxy)pyridin-3-yl)isonicotinamide as a potent dual AChE/GSK3ß inhibitor for the treatment of Alzheimer's disease: Significantly increasing the level of acetylcholine in the brain without affecting that in intestine.
Eur J Med Chem
; 223: 113663, 2021 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34198150
16.
Design, Bio-evaluation and Molecular Dynamics Simulation of Novel GSK-3ß Inhibitors.
Mol Inform
; 40(12): e2060031, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34323388
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