Detalles de la búsqueda
1.
Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.
Nat Immunol
; 24(9): 1540-1551, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37563310
2.
Author Correction: Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets.
Nat Immunol
; 24(11): 1960, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37679551
3.
An atlas of genetic scores to predict multi-omic traits.
Nature
; 616(7955): 123-131, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36991119
4.
The impact of circulating protein levels identified by affinity proteomics on short-term, overall breast cancer risk.
Br J Cancer
; 130(4): 620-627, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38135714
5.
Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization.
Circulation
; 145(16): 1205-1217, 2022 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35300523
6.
Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases.
Clin Proteomics
; 20(1): 31, 2023 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37550624
7.
Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes: Meta-Analyses and Mendelian Randomization Analyses.
Arterioscler Thromb Vasc Biol
; 41(5): 1777-1788, 2021 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33657885
8.
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.
PLoS Genet
; 13(4): e1006706, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28369058
9.
Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib.
Circulation
; 137(10): 999-1010, 2018 03 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28974520
10.
Associations of Circulating Protein Levels With Lipid Fractions in the General Population.
Arterioscler Thromb Vasc Biol
; 38(10): 2505-2518, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30354202
11.
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.
Hum Mol Genet
; 25(9): 1867-74, 2016 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26908601
12.
Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk Factors.
Circulation
; 133(13): 1230-9, 2016 Mar 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-26896437
13.
Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline.
Thorax
; 72(5): 400-408, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28174340
14.
Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.
PLoS Genet
; 10(5): e1004314, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24786987
15.
Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity.
BMC Genet
; 17(1): 116, 2016 08 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27514831
16.
Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.
PLoS Genet
; 9(4): e1003444, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23593036
17.
Genes contributing to pain sensitivity in the normal population: an exome sequencing study.
PLoS Genet
; 8(12): e1003095, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23284290
18.
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Circulation
; 128(12): 1310-24, 2013 Sep 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-23969696
19.
Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8.
J Mol Biol
; 436(2): 168383, 2024 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38070861
20.
ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction.
RSC Adv
; 14(19): 13083-13094, 2024 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38655474