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1.
Acridinium-conjugated aromatic heterocycles as highly potent FtsZ inhibitors: Design, synthesis, and biological evaluation.
Arch Pharm (Weinheim)
; 355(6): e2100400, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35267210
2.
Design, synthesis, biological evaluation and molecular dynamics simulation studies of imidazolidine-2,4-dione derivatives as novel PTP1B inhibitors.
Biochem Biophys Res Commun
; 579: 40-46, 2021 11 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34583194
3.
Exploring the dynamic mechanism of allosteric drug SHP099 inhibiting SHP2E69K.
Mol Divers
; 25(3): 1873-1887, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-33392964
4.
Identification of protein tyrosine phosphatase 1B (PTP1B) inhibitors through De Novo Evoluton, synthesis, biological evaluation and molecular dynamics simulation.
Biochem Biophys Res Commun
; 526(1): 273-280, 2020 05 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-32209254
5.
Scaffold-based selective SHP2 inhibitors design using core hopping, molecular docking, biological evaluation and molecular simulation.
Bioorg Chem
; 105: 104391, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33113413
6.
Design, synthesis and biological evaluation of pyridine derivatives as selective SHP2 inhibitors.
Bioorg Chem
; 100: 103875, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32380342
7.
Design, Synthesis, and Biological Evaluation of 2-Phenoxyalkylhydrazide Benzoxazole Derivatives as Quorum Sensing Inhibitors with Strong Antibiofilm Effect.
J Med Chem
; 67(7): 5721-5743, 2024 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38564271
8.
Design and Synthesis of 4-Fluorophenyl-5-methylene-2(5H)-furanone Derivatives as Potent Quorum Sensing Inhibitors.
J Med Chem
; 66(13): 8441-8463, 2023 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37310919
9.
Exploration of the inhibitory mechanism of PC190723 on FtsZ protein by molecular dynamics simulation.
J Mol Graph Model
; 114: 108189, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35453046
10.
Identification of the potential dual inhibitor of protein tyrosine phosphatase sigma and leukocyte common antigen-related phosphatase by virtual screen, molecular dynamic simulations and post-analysis.
J Biomol Struct Dyn
; 39(1): 45-62, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-31842717
11.
Design, synthesis, biological evaluation and molecular dynamics of LAR inhibitors.
Comput Biol Chem
; 92: 107481, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33838390
12.
Exploring the mechanism of the potent allosteric inhibitor compound2 on SHP2 WT and SHP2F285S by molecular dynamics study.
J Mol Graph Model
; 103: 107807, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33338846
13.
Identification of novel inhibitor of protein tyrosine phosphatases delta: structure-based pharmacophore modeling, virtual screening, flexible docking, molecular dynamics simulation, and post-molecular dynamics analysis.
J Biomol Struct Dyn
; 38(15): 4432-4448, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31625456
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