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1.
Discovery and Characterization of Selective, First-in-Class Inhibitors of Citron Kinase.
J Med Chem
; 67(4): 2631-2666, 2024 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38330278
2.
Characterization of a novel positive allosteric modulator of the α1A-Adrenergic receptor.
Curr Res Pharmacol Drug Discov
; 4: 100142, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36544813
3.
SARS-CoV-2 3CL-protease inhibitors derived from ML300: investigation of P1 and replacements of the 1,2,3-benzotriazole.
Res Sq
; 2023 May 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37214977
4.
Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase.
Cancer Res
; 83(24): 4142-4160, 2023 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37801613
5.
Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CLpro).
J Med Chem
; 65(4): 2880-2904, 2022 02 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34347470
6.
Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC Inhibitors Using Fragment-Based Methods and Structure-Based Design.
J Med Chem
; 63(8): 4315-4333, 2020 04 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32223236
7.
Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core.
J Med Chem
; 63(2): 656-675, 2020 01 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31858797
8.
Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
J Med Chem
; 62(24): 11232-11259, 2019 12 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31724864
9.
Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity.
Cell Rep
; 26(11): 2916-2928.e13, 2019 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30865883
10.
Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design.
J Med Chem
; 61(13): 5623-5642, 2018 07 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-29889518
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