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1.
Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity.
J Med Chem
; 45(11): 2127-30, 2002 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-12014950
2.
An antibody to IP-10 is a potent antagonist of cell migration in vitro and in vivo and does not affect disease in several animal models of inflammation.
Autoimmunity
; 42(3): 171-82, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19301198
3.
Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors.
Bioorg Med Chem Lett
; 17(5): 1233-7, 2007 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17197177
4.
Collagen and aggrecan degradation is blocked in interleukin-1-treated cartilage explants by an inhibitor of IkappaB kinase through suppression of metalloproteinase expression.
J Pharmacol Exp Ther
; 315(1): 382-8, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16009742
5.
Reductively activated disulfide prodrugs of paclitaxel.
Bioorg Med Chem Lett
; 12(24): 3591-4, 2002 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-12443783
6.
BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.
J Biol Chem
; 278(3): 1450-6, 2003 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-12403772
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