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1.
Preclinical investigation of tolerance and antitumour activity of new fluorodeoxyglucose-coupled chlorambucil alkylating agents.
Invest New Drugs
; 29(3): 424-33, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20033262
2.
Evaluation of new iodinated acridine derivatives for targeted radionuclide therapy of melanoma using 125I, an Auger electron emitter.
Invest New Drugs
; 29(6): 1253-63, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20567996
3.
First ex vivo study demonstrating that 99mTc-NTP 15-5 radiotracer binds to human articular cartilage.
Eur J Nucl Med Mol Imaging
; 38(11): 2077-82, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21814851
4.
Targeted radionuclide therapy of melanoma: anti-tumoural efficacy studies of a new 131I labelled potential agent.
Int J Cancer
; 125(3): 708-16, 2009 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19437532
5.
Synthesis, radiosynthesis, and biological evaluation of new proteasome inhibitors in a tumor targeting approach.
J Med Chem
; 51(4): 1043-7, 2008 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-18237109
6.
Evaluation of radiolabeled (hetero)aromatic analogues of N-(2-diethylaminoethyl)-4-iodobenzamide for imaging and targeted radionuclide therapy of melanoma.
J Med Chem
; 51(11): 3133-44, 2008 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-18481842
7.
PP2A activity is controlled by methylation and regulates oncoprotein expression in melanoma cells: a mechanism which participates in growth inhibition induced by chloroethylnitrosourea treatment.
Int J Oncol
; 32(1): 49-57, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18097542
8.
Melanoma affinity in mice and immunosuppressed sheep of [(125)I]N-(4-dipropylaminobutyl)-4-iodobenzamide, a new targeting agent.
Nucl Med Biol
; 35(7): 783-91, 2008 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-18848663
9.
Synthesis and cytotoxic properties of new fluorodeoxyglucose-coupled chlorambucil derivatives.
Bioorg Med Chem
; 16(9): 5004-20, 2008 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18424156
10.
Design, synthesis and preliminary biological evaluation of acridine compounds as potential agents for a combined targeted chemo-radionuclide therapy approach to melanoma.
Bioorg Med Chem
; 16(16): 7671-90, 2008 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18656367
11.
Development of a high-performance liquid chromatographic method for the determination of a new potent radioiodinated melanoma imaging and therapeutic agent.
J Chromatogr B Analyt Technol Biomed Life Sci
; 875(2): 411-8, 2008 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18838313
12.
Liver protein synthesis stays elevated after chemotherapy in tumour-bearing mice.
Cancer Lett
; 239(1): 78-83, 2006 Jul 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-16140458
13.
CENU treatment induced bystander effects which are effective on parental and non-parental tumors and have a phospholipid metabolism proton NMR spectroscopy signature.
Int J Oncol
; 29(3): 637-42, 2006 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-16865279
14.
Melanoma tumors acquire a new phospholipid metabolism phenotype under cystemustine as revealed by high-resolution magic angle spinning proton nuclear magnetic resonance spectroscopy of intact tumor samples.
Cancer Res
; 62(6): 1890-7, 2002 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-11912170
15.
Antiangiogenic and antitumoral activity of phenyl-3-(2-chloroethyl)ureas: a class of soft alkylating agents disrupting microtubules that are unaffected by cell adhesion-mediated drug resistance.
Cancer Res
; 64(13): 4654-63, 2004 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15231678
16.
Chemotherapy inhibits skeletal muscle ubiquitin-proteasome-dependent proteolysis.
Cancer Res
; 62(10): 2771-7, 2002 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12019153
17.
Preliminary studies of new proteasome inhibitors in the tumor targeting approach: synthesis and in vitro cytotoxicity.
J Med Chem
; 48(21): 6731-40, 2005 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-16220988
18.
Long-term disease-free survival in advanced melanomas treated with nitrosoureas: mechanisms and new perspectives.
BMC Cancer
; 5: 147, 2005 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16287507
19.
Uptake in melanoma cells of N-(2-diethylaminoethyl)-2-iodobenzamide (BZA2), an imaging agent for melanoma staging: relation to pigmentation.
Nucl Med Biol
; 32(5): 451-8, 2005 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-15982575
20.
Synthesis, in vitro binding and biodistribution in B16 melanoma-bearing mice of new iodine-125 spermidine benzamide derivatives.
Nucl Med Biol
; 32(4): 377-84, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15878507