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1.
Generation of gene-targeted mice using embryonic stem cells derived from a transgenic mouse model of Alzheimer's disease.
Transgenic Res
; 22(3): 537-47, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22961199
2.
Upregulation of CREB-mediated transcription enhances both short- and long-term memory.
J Neurosci
; 31(24): 8786-802, 2011 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21677163
3.
A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's disease.
J Neurosci
; 30(33): 11157-66, 2010 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-20720123
4.
A novel orally active HDAC6 inhibitor T-518 shows a therapeutic potential for Alzheimer's disease and tauopathy in mice.
Sci Rep
; 11(1): 15423, 2021 07 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-34326423
5.
Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-Indole Derivatives as a Novel Positron Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain.
J Med Chem
; 64(16): 11990-12002, 2021 08 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-34347478
6.
T-495, a novel low cooperative M1 receptor positive allosteric modulator, improves memory deficits associated with cholinergic dysfunction and is characterized by low gastrointestinal side effect risk.
Pharmacol Res Perspect
; 8(1): e00560, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31990455
7.
Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging.
J Neurosci
; 28(40): 9910-9, 2008 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18829949
8.
Ameliorative effects of a non-competitive BACE1 inhibitor TAK-070 on Aß peptide levels and impaired learning behavior in aged rats.
Brain Res
; 1361: 146-56, 2010 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-20849831
9.
Transgenic up-regulation of alpha-CaMKII in forebrain leads to increased anxiety-like behaviors and aggression.
Mol Brain
; 2: 6, 2009 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-19257910
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