Detalles de la búsqueda
1.
Performance and Sensitivity of [99mTc]Tc-sestamibi Compared with Positron Emission Tomography Radiotracers to Measure P-glycoprotein Function in the Kidneys and Liver.
Mol Pharm
; 21(2): 932-943, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38225758
2.
Positron Emission Tomography-Based Pharmacokinetic Analysis To Assess Renal Transporter-Mediated Drug-Drug Interactions of Antimicrobial Drugs.
Antimicrob Agents Chemother
; 67(3): e0149322, 2023 03 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36786609
3.
Dissimilar Effect of P-Glycoprotein and Breast Cancer Resistance Protein Inhibition on the Distribution of Erlotinib to the Retina and Brain in Humans and Mice.
Mol Pharm
; 20(11): 5877-5887, 2023 11 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37883694
4.
Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice.
Int J Mol Sci
; 23(12)2022 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35742960
5.
Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [11C]Metoclopramide in Mice.
Pharm Res
; 38(1): 127-140, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33559045
6.
In vivo characterization of [18F]AVT-011 as a radiotracer for PET imaging of multidrug resistance.
Eur J Nucl Med Mol Imaging
; 47(8): 2026-2035, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31729540
7.
Measurement of Hepatic ABCB1 and ABCG2 Transport Activity with [11C]Tariquidar and PET in Humans and Mice.
Mol Pharm
; 17(1): 316-326, 2020 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31790256
8.
Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model.
Int J Mol Sci
; 21(21)2020 Nov 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33153231
9.
Generation and Characterization of an Abcc1 Humanized Mouse Model (hABCC1flx/flx ) with Knockout Capability.
Mol Pharmacol
; 96(2): 138-147, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31189668
10.
Cross-Isotopic Bioorthogonal Tools as Molecular Twins for Radiotheranostic Applications.
Chembiochem
; 20(12): 1530-1535, 2019 06 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30742739
11.
Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib.
Mol Pharm
; 16(3): 1282-1293, 2019 03 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30694684
12.
Hepatocyte-Specific Deletion of EGFR in Mice Reduces Hepatic Abcg2 Transport Activity Measured by [11C]erlotinib and Positron Emission Tomography.
Drug Metab Dispos
; 45(10): 1093-1100, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28790147
13.
[18F]Fluoroalkyl azides for rapid radiolabeling and (Re)investigation of their potential towards in vivo click chemistry.
Org Biomol Chem
; 15(28): 5976-5982, 2017 Jul 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-28678258
14.
Design, Synthesis, and Evaluation of a Low-Molecular-Weight (11)C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry.
Bioconjug Chem
; 27(7): 1707-12, 2016 Jul 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-27308894
15.
Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-ß-d-allofuranosyl)-2-nitroimidazole (ß-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.
Bioorg Med Chem
; 24(21): 5326-5339, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27614920
16.
Factors Governing P-Glycoprotein-Mediated Drug-Drug Interactions at the Blood-Brain Barrier Measured with Positron Emission Tomography.
Mol Pharm
; 12(9): 3214-25, 2015 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26202880
17.
[11C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier.
J Cereb Blood Flow Metab
; 44(1): 142-152, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37728771
18.
Functionalization of 68Ga-Radiolabeled Nanodiamonds with Octreotide Does Not Improve Tumor-Targeting Capabilities.
Pharmaceuticals (Basel)
; 17(4)2024 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38675474
19.
Advancing 6-bromo-7-[11C]methylpurine to clinical use: improved regioselective radiosynthesis, non-clinical toxicity data and human dosimetry estimates.
EJNMMI Radiopharm Chem
; 9(1): 34, 2024 Apr 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38683266
20.
St. John's wort extract with a high hyperforin content does not induce P-glycoprotein activity at the human blood-brain barrier.
Clin Transl Sci
; 17(5): e13804, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38700454