Detalles de la búsqueda
1.
Carbonylbis(hydrazine-1-carbothioamide) derivatives as a new class of α-glucosidase inhibitors and their mechanistic insights via molecular docking and dynamic simulations.
Arch Pharm (Weinheim)
; 357(3): e2300604, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38148299
2.
Synthesis of the chromone-thiosemicarbazone scaffold as promising α-glucosidase inhibitors: An in vitro and in silico approach toward antidiabetic drug design.
Arch Pharm (Weinheim)
; : e2400140, 2024 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38687119
3.
Chemical Composition of Piper nigrum L. Cultivar Guajarina Essential Oils and Their Biological Activity.
Molecules
; 29(5)2024 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38474459
4.
Synthesis, biological evaluation and molecular modelling of 3-Formyl-6-isopropylchromone derived thiosemicarbazones as α-glucosidase inhibitors.
Bioorg Chem
; 139: 106739, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37478545
5.
Theoretical and Anti-Klebsiella pneumoniae Evaluations of Substituted 2,7-dimethylimidazo[1,2-a]pyridine-3-carboxamide and Imidazopyridine Hydrazide Derivatives.
Molecules
; 28(6)2023 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-36985773
6.
Chemical Composition, Preliminary Toxicity, and Antioxidant Potential of Piper marginatum Sensu Lato Essential Oils and Molecular Modeling Study.
Molecules
; 28(15)2023 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37570784
7.
A sustainable approach towards the three-component synthesis of unsubstituted 1H-imidazoles in the water at ambient conditions.
J Asian Nat Prod Res
; 23(7): 712-716, 2021 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32400182
8.
From lab to nature: Recent advancements in the journey of gastroprotective agents from medicinal chemistry to phytotherapy.
Eur J Med Chem
; 272: 116436, 2024 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38704935
9.
Mechanistic QSAR modeling derived virtual screening, drug repurposing, ADMET and in-vitro evaluation to identify anticancer lead as lysine-specific demethylase 5a inhibitor.
J Biomol Struct Dyn
; : 1-31, 2024 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38385447
10.
Synthesis and antiproliferative evaluation of novel 3,5,8-trisubstituted coumarins against breast cancer.
Future Med Chem
; 2024 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38708686
11.
Structural, dynamic behaviour, in-vitro and computational investigations of Schiff's bases of 1,3-diphenyl urea derivatives against SARS-CoV-2 spike protein.
Sci Rep
; 14(1): 12588, 2024 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38822113
12.
Synthesis, Computational Analysis, Antimicrobial, Antioxidant, Trypan Blue Exclusion Assay, ß-hematin Assay and Anti-inflammatory Studies of some Hydrazones (Part-I).
Curr Comput Aided Drug Des
; 19(2): 108-122, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36177631
13.
Repositioning Cannabinoids and Terpenes as Novel EGFR-TKIs Candidates for Targeted Therapy Against Cancer: A virtual screening model using CADD and biophysical simulations.
Heliyon
; 9(4): e15545, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-37128337
14.
Neuroprotective potential of cannabidiol: Molecular mechanisms and clinical implications.
J Integr Med
; 21(3): 236-244, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36973157
15.
Extensive Multiple 2D-/3D-QSAR Modeling, Molecular Docking and Pharmacophoric Approaches for Piperazinylquinoline Derivatives as Respiratory Syncytial Virus Fusion Inhibitors.
Recent Adv Antiinfect Drug Discov
; 18(2): 148-167, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36424780
16.
The anti-SARS-CoV-2 activity of novel 9, 10-dihydrophenanthrene derivatives: an insight into molecular docking, ADMET analysis, and molecular dynamics simulation.
Sci Afr
; 21: e01754, 2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37332393
17.
Targeting SmCB1: Perspectives and Insights to Design Antischistosomal Drugs.
Curr Med Chem
; 2023 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-37921174
18.
MeltSerts technology (brinzolamide ocular inserts via hot-melt extrusion): QbD-steered development, molecular dynamics, in vitro, ex vivo and in vivo studies.
Int J Pharm
; 648: 123579, 2023 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37931727
19.
Cyclohexane-1,3-dione Derivatives as Future Therapeutic Agents for NSCLC: QSAR Modeling, In Silico ADME-Tox Properties, and Structure-Based Drug Designing Approach.
ACS Omega
; 8(4): 4294-4319, 2023 Jan 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-36743017
20.
L-Proline: A Versatile Organo-Catalyst in Organic Chemistry.
Comb Chem High Throughput Screen
; 26(6): 1108-1140, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-35864793