Detalles de la búsqueda
1.
Reactivators of butyrylcholinesterase inhibited by organophosphorus compounds.
Bioorg Chem
; 150: 107526, 2024 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38878749
2.
Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.
Arch Toxicol
; 2024 May 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-38789714
3.
Direct Chiral Supercritical Fluid Chromatography-Mass Spectrometry Analysis of Monoacylglycerol and Diacylglycerol Isomers for the Study of Lipase-Catalyzed Hydrolysis of Triacylglycerols.
Anal Chem
; 95(11): 5109-5116, 2023 03 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36893116
4.
Strategies for enhanced bioavailability of oxime reactivators in the central nervous system.
Arch Toxicol
; 97(11): 2839-2860, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37642747
5.
Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells.
Arch Toxicol
; 97(11): 2943-2954, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37639014
6.
Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK).
J Enzyme Inhib Med Chem
; 38(1): 2237209, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37489050
7.
Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides.
J Enzyme Inhib Med Chem
; 37(1): 760-767, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35193448
8.
Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening.
Chem Res Toxicol
; 34(3): 699-703, 2021 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33566584
9.
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase.
Arch Toxicol
; 95(3): 985-1001, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33517499
10.
Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates.
J Enzyme Inhib Med Chem
; 36(1): 437-449, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33467931
11.
Design, synthesis, and in vitro evaluation of BP-1-102 analogs with modified hydrophobic fragments for STAT3 inhibition.
J Enzyme Inhib Med Chem
; 36(1): 410-424, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33440995
12.
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators.
J Enzyme Inhib Med Chem
; 35(1): 478-488, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31910701
13.
Wide-Antimicrobial Spectrum of Picolinium Salts.
Molecules
; 25(9)2020 May 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32403238
14.
Oxime K203: a drug candidate for the treatment of tabun intoxication.
Arch Toxicol
; 93(3): 673-691, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30564897
15.
Profiling donepezil template into multipotent hybrids with antioxidant properties.
J Enzyme Inhib Med Chem
; 33(1): 583-606, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29529892
16.
Novel Group of AChE Reactivators-Synthesis, In Vitro Reactivation and Molecular Docking Study.
Molecules
; 23(9)2018 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30205495
17.
Rational Design of a New Class of Toll-Like Receptor 4 (TLR4) Tryptamine Related Agonists by Means of the Structure- and Ligand-Based Virtual Screening for Vaccine Adjuvant Discovery.
Molecules
; 23(1)2018 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29300367
18.
Synthesis, antimicrobial evaluation and molecular modeling of 5-hydroxyisoquinolinium salt series; the effect of the hydroxyl moiety.
Bioorg Med Chem
; 24(4): 841-8, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26774252
19.
SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides.
Arch Toxicol
; 90(12): 2831-2859, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27582056
20.
Synthesis and disinfection effect of the pyridine-4-aldoxime based salts.
Molecules
; 20(3): 3681-96, 2015 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-25719739