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1.
Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability.
ACS Med Chem Lett
; 6(1): 68-72, 2015 Jan 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-25589933
2.
ATP-competitive inhibitors of the mammalian target of rapamycin: design and synthesis of highly potent and selective pyrazolopyrimidines.
J Med Chem
; 52(16): 5013-6, 2009 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-19645448
3.
Discovery of potent and selective inhibitors of the mammalian target of rapamycin (mTOR) kinase.
J Med Chem
; 52(22): 7081-9, 2009 Nov 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-19848404
4.
Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin.
Cancer Res
; 69(15): 6232-40, 2009 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19584280
5.
Discovery of 4-morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as highly potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 6-aryl substituent.
J Med Chem
; 52(24): 8010-24, 2009 Dec 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-19894727
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