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1.
FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.
EMBO J
; 35(20): 2192-2212, 2016 10 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27625374
2.
Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia.
Genome Biol
; 25(1): 143, 2024 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-38822412
3.
The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro.
J Pathol
; 226(3): 451-62, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22009481
4.
IFNγ directly counteracts imatinib-induced apoptosis of primary human CD34+ CML stem/progenitor cells potentially through the upregulation of multiple key survival factors.
Oncoimmunology
; 11(1): 2109861, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35979386
5.
Combination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells.
Cell Death Dis
; 12(10): 875, 2021 09 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-34564697
6.
Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities.
Genome Med
; 12(1): 99, 2020 11 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-33218352
7.
The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.
Cancer Res
; 67(12): 5611-6, 2007 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17575125
8.
Editorial: Ubiquitin-Modifying Enzymes as Drug Targets and Biomarkers in Cancer.
Front Oncol
; 11: 758983, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34604098
9.
Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene.
Oncogene
; 23(35): 5941-9, 2004 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-15208682
10.
TRIM16 inhibits neuroblastoma cell proliferation through cell cycle regulation and dynamic nuclear localization.
Cell Cycle
; 12(6): 889-98, 2013 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23422002
11.
CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer.
EMBO Mol Med
; 5(7): 1067-86, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23776131
12.
TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members.
PLoS One
; 7(5): e37470, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22629402
13.
Both SCF(Cdc4alpha) and SCF(Cdc4gamma) are required for cyclin E turnover in cell lines that do not overexpress cyclin E.
Cell Cycle
; 7(8): 1075-82, 2008 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18414042
14.
RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies.
Proc Natl Acad Sci U S A
; 101(14): 4906-11, 2004 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-15051889
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