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1.
Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aß1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells.
Pharmaceuticals (Basel)
; 12(2)2019 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31234364
2.
Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas.
Neuropharmacology
; 55(5): 743-54, 2008 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-18602930
3.
Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist.
J Med Chem
; 58(18): 7526-48, 2015 Sep 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-26313429
4.
Synthesis and pharmacological characterization of C4-disubstituted analogs of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: identification of a potent, selective metabotropic glutamate receptor agonist and determination of agonist-bound human mGlu2 and mGlu3 amino terminal domain structures.
J Med Chem
; 58(4): 1776-94, 2015 Feb 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-25602126
5.
Discovery and SAR studies of novel GlyT1 inhibitors.
Bioorg Med Chem Lett
; 17(18): 5233-8, 2007 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17629697
6.
Discovery and structure-activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors.
Bioorg Med Chem Lett
; 15(3): 699-703, 2005 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15664840
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