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1.
Vaccine Efficacy in Adults in a Respiratory Syncytial Virus Challenge Study.
N Engl J Med
; 386(25): 2377-2386, 2022 06 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-35731653
2.
Neonatal intermittent hypoxia, fish oil, and/or antioxidant supplementation on gut microbiota in neonatal rats.
Pediatr Res
; 92(1): 109-117, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-34455420
3.
Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain.
Biologicals
; 74: 16-23, 2021 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-34620540
4.
The Effect of Influenza Virus on the Human Oropharyngeal Microbiome.
Clin Infect Dis
; 68(12): 1993-2002, 2019 05 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-30445563
5.
The human viral challenge model: accelerating the evaluation of respiratory antivirals, vaccines and novel diagnostics.
Respir Res
; 19(1): 123, 2018 06 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-29929556
6.
Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adults.
Sci Immunol
; 9(92): eadj9285, 2024 Sep 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38335268
7.
Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study.
Lancet Microbe
; 4(8): e579-e590, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37307844
8.
Human infection studies: Key considerations for challenge agent development and production.
Wellcome Open Res
; 7: 140, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35505774
9.
Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults.
Nat Med
; 28(5): 1031-1041, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35361992
10.
Viral load drives disease in humans experimentally infected with respiratory syncytial virus.
Am J Respir Crit Care Med
; 182(10): 1305-14, 2010 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20622030
11.
Effects of omega 3 polyunsaturated fatty acids, antioxidants, and/or non-steroidal inflammatory drugs in the brain of neonatal rats exposed to intermittent hypoxia.
Int J Dev Neurosci
; 81(5): 448-460, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-33969544
12.
Inhibition of viral and bacterial trigger-stimulated prostaglandin E2 by a throat lozenge containing flurbiprofen: An in vitro study using a human respiratory epithelial cell line.
SAGE Open Med
; 8: 2050312120960568, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33029351
13.
The manufacturing of human viral challenge agents for use in clinical studies to accelerate the drug development process.
BMC Res Notes
; 11(1): 620, 2018 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-30157933
14.
The threat of avian influenza H5N1: 'do we have the tools for the job'?
Antivir Chem Chemother
; 18(2): 71-4, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17542151
15.
Correction: Accelerating Influenza Research: Vaccines, Antivirals, Immunomodulators and Monoclonal Antibodies. The Manufacture of a New Wild-Type H3N2 Virus for the Human Viral Challenge Model.
PLoS One
; 11(6): e0157211, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27280602
16.
An Intranasal Proteosome-Adjuvanted Trivalent Influenza Vaccine Is Safe, Immunogenic & Efficacious in the Human Viral Influenza Challenge Model. Serum IgG & Mucosal IgA Are Important Correlates of Protection against Illness Associated with Infection.
PLoS One
; 11(12): e0163089, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-28005959
17.
Accelerating Influenza Research: Vaccines, Antivirals, Immunomodulators and Monoclonal Antibodies. The Manufacture of a New Wild-Type H3N2 Virus for the Human Viral Challenge Model.
PLoS One
; 11(1): e0145902, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26761707
18.
A Tool for Investigating Asthma and COPD Exacerbations: A Newly Manufactured and Well Characterised GMP Wild-Type Human Rhinovirus for Use in the Human Viral Challenge Model.
PLoS One
; 11(12): e0166113, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27936016
19.
A Synthetic Influenza Virus Vaccine Induces a Cellular Immune Response That Correlates with Reduction in Symptomatology and Virus Shedding in a Randomized Phase Ib Live-Virus Challenge in Humans.
Clin Vaccine Immunol
; 22(7): 828-35, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25994549
20.
Intranasal H5N1 vaccines, adjuvanted with chitosan derivatives, protect ferrets against highly pathogenic influenza intranasal and intratracheal challenge.
PLoS One
; 9(5): e93761, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24850536