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1.
Design, synthesis and evaluation of novel indandione derivatives as multifunctional agents with cholinesterase inhibition, anti-ß-amyloid aggregation, antioxidant and neuroprotection properties against Alzheimer's disease.
Bioorg Med Chem
; 24(16): 3829-41, 2016 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27353888
2.
Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
Bioorg Med Chem
; 24(12): 2777-88, 2016 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27157006
3.
Multifunctional novel Diallyl disulfide (DADS) derivatives with ß-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.
Bioorg Med Chem
; 23(19): 6389-403, 2015 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26337018
4.
Synthesis, biological evaluation and molecular docking study of novel piperidine and piperazine derivatives as multi-targeted agents to treat Alzheimer's disease.
Bioorg Med Chem
; 23(5): 1135-48, 2015 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25624107
5.
Novel synthetic analogs of diallyl disulfide triggers cell cycle arrest and apoptosis via ROS generation in MIA PaCa-2 cells.
Pharmacol Rep
; 69(4): 813-821, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28591670
6.
Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease.
Eur J Med Chem
; 125: 736-750, 2017 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27721157
7.
DADS Analogues Ameliorated the Cognitive Impairments of Alzheimer-Like Rat Model Induced by Scopolamine.
Neurotox Res
; 30(3): 407-26, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27149969
8.
Protective effects of a piperazine derivative [N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-phenyl} carbamic acid ethyl ester] against aluminium-induced neurotoxicity: insights from in silico and in vivo studies.
Neurotox Res
; 27(3): 314-27, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25403519
9.
Novel diallyldisulfide analogs ameliorate cardiovascular remodeling in rats with L-NAME-induced hypertension.
Eur J Pharmacol
; 691(1-3): 198-208, 2012 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22819707
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