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1.
Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)-driven Complement-mediated Diseases.
Immunol Rev
; 313(1): 194-216, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36203396
2.
Comprehensive functional characterization of Complement factor I rare variant genotypes identified in the SCOPE Geographic Atrophy cohort.
J Biol Chem
; : 107452, 2024 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38852887
3.
Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study.
Blood
; 142(16): 1371-1386, 2023 10 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-37369098
4.
Gain-of-function factor H-related 5 protein impairs glomerular complement regulation resulting in kidney damage.
Proc Natl Acad Sci U S A
; 118(13)2021 03 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-33753502
5.
Plasminogen activator-coated nanobubbles targeting cellbound ß2-glycoprotein I as a novel thrombus-specific thrombolytic strategy.
Haematologica
; 108(7): 1861-1872, 2023 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36172817
6.
Large-Scale Whole-Genome Sequencing Reveals the Genetic Architecture of Primary Membranoproliferative GN and C3 Glomerulopathy.
J Am Soc Nephrol
; 31(2): 365-373, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31919107
7.
Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy.
Kidney Int
; 97(6): 1260-1274, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32386968
8.
Successful simultaneous liver-kidney transplantation for renal failure associated with hereditary complement C3 deficiency.
Am J Transplant
; 20(8): 2260-2263, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31970896
9.
CD19 is essential for B cell activation by promoting B cell receptor-antigen microcluster formation in response to membrane-bound ligand.
Nat Immunol
; 9(1): 63-72, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18059271
10.
Modulation of the Alternative Pathway of Complement by Murine Factor H-Related Proteins.
J Immunol
; 200(1): 316-326, 2018 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29187587
11.
An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy.
J Am Soc Nephrol
; 29(6): 1649-1661, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29588430
12.
Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface-selective regulation of complement activation.
J Biol Chem
; 292(32): 13345-13360, 2017 08 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28637873
13.
Thrombotic Microangiopathy in Inverted Formin 2-Mediated Renal Disease.
J Am Soc Nephrol
; 28(4): 1084-1091, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27974406
14.
Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland.
Kidney Int
; 92(5): 1261-1271, 2017 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28750931
15.
A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.
J Am Soc Nephrol
; 27(6): 1617-24, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26490391
16.
An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy.
Kidney Int
; 88(6): 1314-1322, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26221753
17.
Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN.
J Am Soc Nephrol
; 25(11): 2425-33, 2014 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24722444
18.
A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome.
Blood
; 119(2): 591-601, 2012 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-22058112
19.
Genotype/phenotype correlations in complement factor H deficiency arising from uniparental isodisomy.
Am J Kidney Dis
; 62(5): 978-83, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23870792
20.
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.
Blood
; 115(2): 379-87, 2010 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19861685