Detalles de la búsqueda
1.
Comparison of Immunoassays for Measuring Serum Levels of Golimumab and Antibodies Against Golimumab in Ulcerative Colitis: A Retrospective Observational Study.
Ther Drug Monit
; 41(4): 459-466, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30817702
2.
The nuclear hormone receptor gene Nr2c1 (Tr2) is a critical regulator of early retina cell patterning.
Dev Biol
; 429(1): 343-355, 2017 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28551284
3.
An open-label, single-dose, phase 1 study of the absorption, metabolism and excretion of quizartinib, a highly selective and potent FLT3 tyrosine kinase inhibitor, in healthy male subjects, for the treatment of acute myeloid leukemia.
Xenobiotica
; 47(10): 856-869, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-27460866
4.
Pharmacokinetics and immunogenicity investigation of a human anti-interleukin-17 monoclonal antibody in non-naïve cynomolgus monkeys.
Drug Metab Dispos
; 43(5): 762-70, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25739974
5.
Historical control histopathology data from amphibian metamorphosis assays and fathead minnow fish short term reproductive assays: A tool for data interpretation.
Aquat Toxicol
; 267: 106811, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38159458
6.
Corrigendum to "The Nuclear Hormone Receptor Nr2c1 (Tr2) is a critical regulator of early retina cell pattering" [Dev. Biol. 16 (2017) 30797-7].
Dev Biol
; 429(1): 370, 2017 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28743516
7.
An Amphibian Metamorphosis Assay Dietary Restriction Study: Lessons for Data Interpretation.
Environ Toxicol Chem
; 42(5): 1061-1074, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36848316
8.
Preclinical evaluation of the metabolism and disposition of RRx-001, a novel investigative anticancer agent.
Drug Metab Dispos
; 40(9): 1810-6, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22699395
9.
Population-level variation in parasite resistance due to differences in immune initiation and rate of response.
Evol Lett
; 6(2): 162-177, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35386836
10.
Pharmacokinetics, pharmacodynamics and safety of a human anti-IL-6 monoclonal antibody (sirukumab) in healthy subjects in a first-in-human study.
Br J Clin Pharmacol
; 72(2): 270-81, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21392075
11.
Population pharmacokinetic modeling of ustekinumab, a human monoclonal antibody targeting IL-12/23p40, in patients with moderate to severe plaque psoriasis.
J Clin Pharmacol
; 49(2): 162-75, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19179295
12.
Recommendations for the Development and Validation of Immunogenicity Assays in Support of Biosimilar Programs.
AAPS J
; 22(1): 7, 2019 12 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31792633
13.
Effects of administration of a monoclonal antibody against mouse tumor necrosis factor alpha during pregnancy and lactation on the pre- and postnatal development of the mouse immune system.
Int J Toxicol
; 27(4): 341-7, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18821398
14.
2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3 - LBA/cell-based assays: immunogenicity, biomarkers and PK assays).
Bioanalysis
; 10(24): 1973-2001, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30488726
15.
Pharmacokinetics and safety of golimumab, a fully human anti-TNF-alpha monoclonal antibody, in subjects with rheumatoid arthritis.
J Clin Pharmacol
; 47(3): 383-96, 2007 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-17322150
16.
Implementing a tiered approach to bioanalytical method validation for large-molecule ligand-binding assay methods in pharmacokinetic assessments.
Bioanalysis
; 9(18): 1407-1422, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28920457
17.
Comparisons of Serum Infliximab and Antibodies-to-Infliximab Tests Used in Inflammatory Bowel Disease Clinical Trials of Remicade®.
AAPS J
; 19(1): 161-171, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27600137
18.
2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as covalent-binding, irreversible inhibitors of the kinase domain of vascular endothelial growth factor receptor-2.
J Med Chem
; 48(24): 7560-81, 2005 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16302797
19.
The structure of gas-phase bradykinin fragment 1-5 (RPPGF) ions: an ion mobility spectrometry and H/D exchange ion-molecule reaction chemistry study.
J Am Soc Mass Spectrom
; 16(6): 893-905, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15878286
20.
Immunogenicity of Guselkumab Is Not Clinically Relevant in Patients with Moderate-to-Severe Plaque Psoriasis.
J Invest Dermatol
; 139(8): 1830-1834.e6, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30851300