Detalles de la búsqueda
1.
Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity.
Mol Pharmacol
; 78(6): 1105-23, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20923853
2.
Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity.
Mol Pharmacol
; 75(3): 577-88, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19047481
3.
Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.
Mol Pharmacol
; 74(5): 1345-58, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18664603
4.
Phenotype risk scores identify patients with unrecognized Mendelian disease patterns.
Science
; 359(6381): 1233-1239, 2018 03 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-29590070
5.
Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record.
PLoS One
; 12(7): e0175508, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28686612
6.
Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins.
J Med Chem
; 52(11): 3445-8, 2009 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-19438238
7.
Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M1) antagonist in vitro and in vivo probe.
Curr Top Med Chem
; 9(13): 1217-26, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19807667
8.
Loss of phosphatase activity in Ptp69D alleles supporting axon guidance defects.
J Cell Biochem
; 98(5): 1296-307, 2006 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16514605
Resultados
1 -
8
de 8
1
Próxima >
>>