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1.
Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response.
Blood
; 132(3): 307-320, 2018 07 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29724897
2.
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation.
J Immunother Cancer
; 11(1)2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36639156
3.
The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.
Nat Commun
; 13(1): 4061, 2022 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35831316
4.
The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma.
Cell Death Dis
; 12(10): 885, 2021 09 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34584066
5.
N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma.
Sci Rep
; 10(1): 7157, 2020 04 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32346009
6.
A Cell-Based MAPK Reporter Assay Reveals Synergistic MAPK Pathway Activity Suppression by MAPK Inhibitor Combination in BRAF-Driven Pediatric Low-Grade Glioma Cells.
Mol Cancer Ther
; 19(8): 1736-1750, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32451331
7.
Design, synthesis and biological evaluation of ß-peptoid-capped HDAC inhibitors with anti-neuroblastoma and anti-glioblastoma activity.
Medchemcomm
; 10(7): 1109-1115, 2019 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31391882
8.
Alkoxyurea-Based Histone Deacetylase Inhibitors Increase Cisplatin Potency in Chemoresistant Cancer Cell Lines.
J Med Chem
; 60(13): 5334-5348, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28581289
9.
Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing.
Oncotarget
; 8(7): 11460-11479, 2017 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-28002790
10.
Design, synthesis and 3D-QSAR studies of novel 1,4-dihydropyridines as TGFß/Smad inhibitors.
Eur J Med Chem
; 95: 249-66, 2015 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-25817775
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