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1.
An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury.
Arch Toxicol
; 95(1): 149-168, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32816093
2.
Transporter-Mediated Disposition, Clinical Pharmacokinetics and Cholestatic Potential of Glyburide and Its Primary Active Metabolites.
Drug Metab Dispos
; 45(7): 737-747, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28438781
3.
Inhibition of Hepatobiliary Transport Activity by the Antibacterial Agent Fusidic Acid: Insights into Factors Contributing to Conjugated Hyperbilirubinemia/Cholestasis.
Chem Res Toxicol
; 29(10): 1778-1788, 2016 Oct 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27676153
4.
Circumventing the Crabtree effect: replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants.
Toxicol Sci
; 97(2): 539-47, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17361016
5.
Assessment of Bile Salt Export Pump (BSEP) Inhibition in Membrane Vesicles Using Radioactive and LC/MS-Based Detection Methods.
Curr Protoc Toxicol
; 71: 14.14.1-14.14.20, 2017 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28146280
6.
Investigation of drug-induced mitochondrial toxicity using fluorescence-based oxygen-sensitive probes.
Toxicol Sci
; 92(1): 186-200, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16638925
7.
Mechanistic investigation of imatinib-induced cardiac toxicity and the involvement of c-Abl kinase.
Toxicol Sci
; 129(1): 188-99, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22641616
8.
Epithelial tissue hyperplasia induced by the RAF inhibitor PF-04880594 is attenuated by a clinically well-tolerated dose of the MEK inhibitor PD-0325901.
Mol Cancer Ther
; 11(10): 2274-83, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22752429
9.
Effect of the multitargeted tyrosine kinase inhibitors imatinib, dasatinib, sunitinib, and sorafenib on mitochondrial function in isolated rat heart mitochondria and H9c2 cells.
Toxicol Sci
; 106(1): 153-61, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18664550
10.
In vitro assessment of mitochondrial dysfunction and cytotoxicity of nefazodone, trazodone, and buspirone.
Toxicol Sci
; 103(2): 335-45, 2008 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18344530
11.
Strategies to reduce late-stage drug attrition due to mitochondrial toxicity.
Expert Rev Mol Diagn
; 7(2): 161-75, 2007 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-17331064
12.
Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions.
J Biol Chem
; 278(46): 45594-602, 2003 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-12944392
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