Detalles de la búsqueda
1.
Current challenges and opportunities for pharmacogenomics: perspective of the Industry Pharmacogenomics Working Group (I-PWG).
Hum Genet
; 141(6): 1165-1173, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-34081195
2.
Evaluation of the Association of Polymorphisms With Palbociclib-Induced Neutropenia: Pharmacogenetic Analysis of PALOMA-2/-3.
Oncologist
; 26(7): e1143-e1155, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33955129
3.
Neutralization of Omicron Subvariant BA.2.75 after Bivalent Vaccination.
N Engl J Med
; 387(23): 2194-2196, 2022 12 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36416761
4.
Neutralization of SARS-CoV-2 Omicron BA.2.75 after mRNA-1273 Vaccination.
N Engl J Med
; 387(13): 1234-1236, 2022 09 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-36083119
5.
Plasma extracellular nanovesicle (exosome)-derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure.
Br J Clin Pharmacol
; 85(1): 216-226, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30340248
6.
Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity.
Eur J Clin Pharmacol
; 75(9): 1211-1218, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31123759
7.
Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries.
Eur J Clin Pharmacol
; 74(7): 913-920, 2018 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-29572563
8.
Field Study and Correlative Studies of Factor IX Variant FIX-R338L in Participants Treated with Fidanacogene Elaparvovec.
Thromb Haemost
; 2024 Jun 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38863155
9.
2023 White Paper on Recent Issues in Bioanalysis: ISR for ADA Assays, the Rise of dPCR vs qPCR, International Reference Standards for Vaccine Assays, Anti-AAV TAb Post-Dose Assessment, NanoString Validation, ELISpot as Gold Standard (Part 3 - Recommendations on Gene Therapy, Cell Therapy, Vaccines Immunogenicity & Technologies; Biotherapeutics Immunogenicity & Risk Assessment; ADA/NAb Assay/Reporting Harmonization).
Bioanalysis
; 16(7): 77-119, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38389403
10.
Mutational basis of serum cross-neutralization profiles elicited by infection or vaccination with SARS-CoV-2 variants.
bioRxiv
; 2023 Aug 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37645950
11.
2022 White Paper on Recent Issues in Bioanalysis: FDA Draft Guidance on Immunogenicity Information in Prescription Drug Labeling, LNP & Viral Vectors Therapeutics/Vaccines Immunogenicity, Prolongation Effect, ADA Affinity, Risk-based Approaches, NGS, qPCR, ddPCR Assays (Part 3 - Recommendations on Gene Therapy, Cell Therapy, Vaccines Immunogenicity & Technologies; Immunogenicity & Risk Assessment of Biotherapeutics and Novel Modalities; NAb Assays Integrated Approach).
Bioanalysis
; 15(14): 773-814, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-37526071
12.
2022 White Paper on Recent Issues in Bioanalysis: Enzyme Assay Validation, BAV for Primary End Points, Vaccine Functional Assays, Cytometry in Tissue, LBA in Rare Matrices, Complex NAb Assays, Spectral Cytometry, Endogenous Analytes, Extracellular Vesicles Part 2 - Recommendations on Biomarkers/CDx, Flow Cytometry, Ligand-Binding Assays Development & Validation; Emerging Technologies; Critical Reagents Deep Characterization.
Bioanalysis
; 15(15): 861-903, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37584363
13.
2021 White Paper on Recent Issues in Bioanalysis: ISR for Biomarkers, Liquid Biopsies, Spectral Cytometry, Inhalation/Oral & Multispecific Biotherapeutics, Accuracy/LLOQ for Flow Cytometry (Part 2 - Recommendations on Biomarkers/CDx Assays Development & Validation, Cytometry Validation & Innovation, Biotherapeutics PK LBA Regulated Bioanalysis, Critical Reagents & Positive Controls Generation).
Bioanalysis
; 14(10): 627-692, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35578974
14.
Meta-Analysis of Noncompartmental Pharmacokinetic Parameters of Ertugliflozin to Evaluate Dose Proportionality and UGT1A9 Polymorphism Effect on Exposure.
J Clin Pharmacol
; 61(9): 1220-1231, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33813736
15.
2020 White Paper on Recent Issues in Bioanalysis: Vaccine Assay Validation, qPCR Assay Validation, QC for CAR-T Flow Cytometry, NAb Assay Harmonization and ELISpot Validation (Part 3 - Recommendations on Immunogenicity Assay Strategies, NAb Assays, Biosimilars and FDA/EMA Immunogenicity Guidance/Guideline, Gene & Cell Therapy and Vaccine Assays).
Bioanalysis
; 13(6): 415-463, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33533276
16.
Clinical-translational strategies for the elevation of Nm23-H1 metastasis suppressor gene expression.
Mol Cell Biochem
; 329(1-2): 115-20, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19387797
17.
Altered gene and protein expression by Nm23-H1 in metastasis suppression.
Mol Cell Biochem
; 329(1-2): 141-8, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19415462
18.
Immune expression and inhibition of heat shock protein 90 in uveal melanoma.
Clin Cancer Res
; 14(3): 847-55, 2008 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18245548
19.
Molecular pathways mediating liver metastasis in patients with uveal melanoma.
Clin Cancer Res
; 14(4): 951-6, 2008 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18281525
20.
Expression of cyclooxygenase-2 in choroidal neovascular membranes from age-related macular degeneration patients.
Retina
; 29(2): 176-80, 2009 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-18827739