Detalles de la búsqueda
1.
HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms.
Blood
; 135(3): 191-207, 2020 01 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-31750881
2.
Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN).
Bioorg Med Chem Lett
; 29(8): 1001-1006, 2019 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30803804
3.
Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11.
Bioorg Med Chem Lett
; 28(12): 2143-2147, 2018 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29776742
4.
Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling.
Bioorg Med Chem
; 24(10): 2215-34, 2016 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27085672
5.
2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitors.
Bioorg Med Chem Lett
; 22(17): 5392-5, 2012 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22877629
6.
Corrigendum to "Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling" [Bioorg. Med. Chem. 24 (2016) 2215-2234].
Bioorg Med Chem
; 24(13): 3093, 2016 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27234892
7.
Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2.
Sci Rep
; 10(1): 4722, 2020 03 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32170113
8.
Discovery of alpha-amidosulfones as potent and selective agonists of CB2: synthesis, SAR, and pharmacokinetic properties.
Bioorg Med Chem Lett
; 19(1): 31-5, 2009 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19062274
9.
Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation.
J Med Chem
; 51(6): 1649-67, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18324761
10.
Novel 2,3-dihydro-1,4-benzoxazines as potent and orally bioavailable inhibitors of tumor-driven angiogenesis.
J Med Chem
; 51(6): 1695-705, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18311900
11.
Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.
J Med Chem
; 51(6): 1637-48, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18278858
12.
Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.
J Med Chem
; 51(6): 1681-94, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18321037
13.
Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2.
Bioorg Med Chem Lett
; 18(15): 4267-74, 2008 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18640038
14.
Echo rounds: Transesophageal echocardiography: identification and management of a misplaced pedicle screw in the descending thoracic aorta after posterior spinal fusion.
Anesth Analg
; 116(2): 303-6, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23302974
15.
Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains.
ACS Med Chem Lett
; 8(8): 847-852, 2017 Aug 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28835800
16.
Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.
J Med Chem
; 49(16): 4981-91, 2006 Aug 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-16884310
17.
Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.
J Med Chem
; 49(19): 5671-86, 2006 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-16970394
18.
Cardiothoracic anesthesiology fellowship: challenges of training and a novel approach to resident education.
J Cardiothorac Vasc Anesth
; 25(6): 1204-6, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-22000984
19.
Structure-Based Design of Potent and Selective CK1γ Inhibitors.
ACS Med Chem Lett
; 3(12): 1059-64, 2012 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900428
20.
Update on lymphocyte specific kinase inhibitors: a patent survey.
Expert Opin Ther Pat
; 20(11): 1573-93, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20831362