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1.
A Phase I, First-in-Human Study of GSK2849330, an Anti-HER3 Monoclonal Antibody, in HER3-Expressing Solid Tumors.
Oncologist
; 26(10): e1844-e1853, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34132450
2.
Inhibition of Intestinal OATP2B1 by the Calcium Receptor Antagonist Ronacaleret Results in a Significant Drug-Drug Interaction by Causing a 2-Fold Decrease in Exposure of Rosuvastatin.
Drug Metab Dispos
; 45(1): 27-34, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27737931
3.
Manufacturing-dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development.
Clin Transl Sci
; 15(11): 2625-2639, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36097345
4.
Safety, Pharmacokinetics, and Pharmacodynamics of the TLR4 Agonist GSK1795091 in Healthy Individuals: Results from a Randomized, Double-blind, Placebo-controlled, Ascending Dose Study.
Clin Ther
; 42(8): 1519-1534.e33, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32739049
5.
Response to ERBB3-Directed Targeted Therapy in NRG1-Rearranged Cancers.
Cancer Discov
; 8(6): 686-695, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29610121
6.
Non invasive imaging assessment of the biodistribution of GSK2849330, an ADCC and CDC optimized anti HER3 mAb, and its role in tumor macrophage recruitment in human tumor-bearing mice.
PLoS One
; 12(4): e0176075, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28448604
7.
Optimizing the in vitro and clinical assessment of drug interaction risk by understanding co-medications in patient populations.
Expert Opin Drug Metab Toxicol
; 9(6): 737-51, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23586918
8.
An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation.
Bone
; 46(2): 534-42, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-19786130
9.
Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues.
Drug Metab Dispos
; 32(9): 1008-14, 2004 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15319343
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