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1.
A Randomized, Placebo-Controlled, Respiratory Syncytial Virus Human Challenge Study of the Antiviral Efficacy, Safety, and Pharmacokinetics of RV521, an Inhibitor of the RSV-F Protein.
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31712214
2.
Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.
J Med Chem
; 64(7): 3658-3676, 2021 04 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33729773
3.
Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach.
Bioorg Med Chem Lett
; 19(15): 4509-14, 2009 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19523822
4.
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.
Bioorg Med Chem Lett
; 19(15): 4504-8, 2009 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19520573
5.
State of the Art in Respiratory Syncytial Virus Drug Discovery and Development.
J Med Chem
; 62(7): 3206-3227, 2019 04 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30411898
6.
Discovery of 4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}-N-(tetrahydro-2H- pyran-4-yl)benzamide (GW788388): a potent, selective, and orally active transforming growth factor-beta type I receptor inhibitor.
J Med Chem
; 49(7): 2210-21, 2006 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-16570917
7.
Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors.
J Med Chem
; 47(18): 4494-506, 2004 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-15317461
8.
Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors.
Bioorg Med Chem Lett
; 14(21): 5445-8, 2004 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15454242
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