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1.
Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors.
Bioorg Med Chem
; 21(24): 7686-98, 2013 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24216091
2.
Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects.
Eur J Med Chem
; 239: 114522, 2022 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35749987
3.
LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models.
Sci Adv
; 7(11)2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33712455
4.
Inhibition of KDM1A activity restores adult neurogenesis and improves hippocampal memory in a mouse model of Kabuki syndrome.
Mol Ther Methods Clin Dev
; 20: 779-791, 2021 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33738331
5.
New Series of Potent Allosteric Inhibitors of Deoxyhypusine Synthase.
ACS Med Chem Lett
; 11(8): 1645-1652, 2020 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-34345355
6.
Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.
J Med Chem
; 63(6): 3215-3226, 2020 03 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-32142284
7.
Cyclization reactions of homopropargyl azide derivatives catalyzed by PtCl4 in ethanol solution: synthesis of functionalized pyrrole derivatives.
Org Lett
; 8(23): 5349-52, 2006 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-17078715
8.
New synthetic method for indole-2-carboxylate and its application to the total synthesis of duocarmycin SA.
Org Lett
; 6(17): 2953-6, 2004 Aug 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-15330656
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