Detalles de la búsqueda
1.
Effect of Paroxetine or Quetiapine Combined With Oxycodone vs Oxycodone Alone on Ventilation During Hypercapnia: A Randomized Clinical Trial.
JAMA
; 328(14): 1405-1414, 2022 10 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36219407
2.
In Vitro Testing of Sunscreens for Dermal Absorption: Method Comparison and Rank Order Correlation with In Vivo Absorption.
AAPS PharmSciTech
; 23(5): 121, 2022 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35459978
3.
Effect of Oral Ranitidine on Urinary Excretion of N-Nitrosodimethylamine (NDMA): A Randomized Clinical Trial.
JAMA
; 326(3): 240-249, 2021 07 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-34180947
4.
Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
JAMA
; 323(3): 256-267, 2020 01 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31961417
5.
Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial.
JAMA
; 321(21): 2082-2091, 2019 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31058986
6.
Development and validation of a LC-MS/MS method for quantitation of fosfomycin - Application to in vitro antimicrobial resistance study using hollow-fiber infection model.
Biomed Chromatogr
; 32(6): e4214, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29461629
7.
Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro.
Drug Metab Dispos
; 44(3): 320-8, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26714763
8.
Lessons learned from regulatory submissions involving endogenous therapeutic analyte bioanalysis.
Bioanalysis
; 16(3): 171-184, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38088828
9.
A Bioanalytical Method for Quantification of N-nitrosodimethylamine (NDMA) in Human Plasma and Urine with Different Meals and following Administration of Ranitidine.
J Pharm Sci
; 112(5): 1315-1323, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36736776
10.
Considerations for Use of Pharmacodynamic Biomarkers to Support Biosimilar Development - (I) A Randomized Trial with PCSK9 Inhibitors.
Clin Pharmacol Ther
; 113(1): 71-79, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36282186
11.
Considerations for Use of Pharmacodynamic Biomarkers to Support Biosimilar Development - (II) A Randomized Trial with IL-5 Antagonists.
Clin Pharmacol Ther
; 113(1): 80-89, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36184697
12.
Considerations for Use of Pharmacodynamic Biomarkers to Support Biosimilar Development - (III) A Randomized Trial with Interferon Beta-1a Products.
Clin Pharmacol Ther
; 113(2): 339-348, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36324229
13.
Evaluating the Utility of Proteomics for the Identification of Circulating Pharmacodynamic Biomarkers of IFNß-1a Biologics.
Clin Pharmacol Ther
; 113(1): 98-107, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36308070
14.
A novel LC-MS/MS method for simultaneous quantification of tenofovir and lamivudine in human plasma and its application to a pharmacokinetic study.
Biomed Chromatogr
; 26(10): 1202-9, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22222724
15.
hERG block potencies for 5 positive control drugs obtained per ICH E14/S7B Q&As best practices: Impact of recording temperature and drug loss.
J Pharmacol Toxicol Methods
; 117: 107193, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35792285
16.
Determination of five positive control drugs in hERG external solution (buffer) by LC-MS/MS to support in vitro hERG assay as recommended by ICH S7B.
J Pharmacol Toxicol Methods
; 118: 107229, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36334898
17.
New science, drug regulation, and emergent public health issues: The work of FDA's division of applied regulatory science.
Front Med (Lausanne)
; 9: 1109541, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36743666
18.
Novel simultaneous method for the determination of avobenzone and oxybenzone in human plasma by UHPLC-MS/MS with phospholipid removal pretreatment: An application to a sunscreen clinical trial.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1169: 122615, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33706185
19.
Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation.
Clin Transl Sci
; 14(3): 1049-1061, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33382907
20.
Effects of sedative psychotropic drugs combined with oxycodone on respiratory depression in the rat.
Clin Transl Sci
; 14(6): 2208-2219, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34080766